Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription requires phosphorylation of the nucleolar trasnscription factor UBF

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

1990 • 656 citations

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis

1988 • 361 citations

The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation.

1992 • 195 citations

Localization of the RNA polymerase I transcription factor hUBF during the cell cycle

1993 • 178 citations

Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo.

1981 • 159 citations

Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription.

1992 • 159 citations

Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties.

1992 • 132 citations

Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I.

1991 • 125 citations

Identification of two forms of the RNA polymerase I transcription factor UBF.

1991 • 120 citations

Dual role of the nucleolar transcription factor UBF: trans-activator and antirepressor.

1992 • 110 citations

The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes

1993 • 102 citations

Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.

1994 • 98 citations

A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I

1993 • 95 citations

xUBF contains a novel dimerization domain essential for RNA polymerase I transcription.

1991 • 83 citations

Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2

1992 • 81 citations

The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription

1993 • 80 citations

Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF

1991 • 76 citations

The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I.

1994 • 70 citations

The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein.

1994 • 52 citations

Sequence-specific transactivators counteract topoisomerase II-mediated inhibition ofin vitrotranscription by RNA polymerases I and II

1993 • 34 citations