Agonist‐Independent Internalization and Activity of a C‐Terminally Truncated Somatostatin Receptor Subtype 2(δ349)

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

1993 • 1,213 citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

1996 • 938 citations

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.

1989 • 920 citations

Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization

1988 • 429 citations

Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation.

1996 • 377 citations

Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization.

1995 • 343 citations

Structural Instability of a Constitutively Active G Protein-coupled Receptor

1997 • 285 citations

Locating ligand-binding sites in 7tm receptors by protein engineering

1994 • 282 citations

Constitutively active mutants of the alpha 2-adrenergic receptor

1993 • 234 citations

Carboxyl-terminal Splicing of the Rat μ Opioid Receptor Modulates Agonist-mediated Internalization and Receptor Resensitization

1998 • 190 citations

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.

1995 • 176 citations

Agonist-induced Desensitization, Internalization, and Phosphorylation of the sst2A Somatostatin Receptor

1997 • 156 citations

Differential Internalization of Somatostatin in COS-7 Cells Transfected with SST₁and SST₂Receptor Subtypes: A Confocal Microscopic Study Using Novel Fluorescent Somatostatin Derivatives¹

1997 • 110 citations

Phosphorylation of Four Amino Acid Residues in the Carboxyl Terminus of the Rat Somatostatin Receptor Subtype 3 Is Crucial for Its Desensitization and Internalization

1997 • 95 citations

Coupling of rat somatostatin receptor subtypes to a G‐protein gated inwardly rectifying potassium channel (GIRK1)

1997 • 83 citations

Processing pathway for protease B of Saccharomyces cerevisiae.

1989 • 81 citations

Development of selective antibodies against the human somatostatin receptor subtypes sst1–sst5

1997 • 79 citations

Endocytosis of the Rat Somatostatin Receptors: Subtype Discrimination, Ligand Specificity, and Delineation of Carboxy-Terminal Positive and Negative Sequence Motifs

1997 • 73 citations

A Constitutively Internalizing and Recycling Mutant of the μ‐Opioid Receptor

1997 • 68 citations

A Receptor-G Protein Coupling-independent Step in the Internalization of the Thyrotropin-releasing Hormone Receptor

1997 • 49 citations

Truncation of the Thyrotropin-releasing Hormone Receptor Carboxyl Tail Causes Constitutive Activity and Leads to Impaired Responsiveness in Xenopus Oocytes and AtT20 Cells

1995 • 43 citations

Differential Internalization of Somatostatin in COS-7 Cells Transfected with SST1 and SST2 Receptor Subtypes: A Confocal Microscopic Study Using Novel Fluorescent Somatostatin Derivatives

1997 • 38 citations

Rat Somatostatin Receptor Subtype 4 Can Be Made Sensitive to Agonist-Induced Internalization by Mutation of a Single Threonine (Residue 331)

1998 • 36 citations