On the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4 ⁺ T cells

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

IL-7 is critical for homeostatic proliferation and survival of naïve T cells

2001 • 940 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

Mice lacking MHC class II molecules

1991 • 869 citations

The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

1999 • 742 citations

Selecting and maintaining a diverse T-cell repertoire

1999 • 712 citations

Low-Affinity Ligands for the TCR Drive Proliferation of Mature CD8+ T Cells in Lymphopenic Hosts

1999 • 548 citations

Homeostasis-Stimulated Proliferation Drives Naive T Cells to Differentiate Directly into Memory T Cells

2000 • 527 citations

Cutting Edge: Naive T Cells Masquerading as Memory Cells

2000 • 476 citations

Class II-Independent Generation of CD4 Memory T Cells from Effectors

1999 • 422 citations

Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

1997 • 419 citations

Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells

1997 • 402 citations

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.

1995 • 393 citations

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1996 • 377 citations

Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

1999 • 341 citations

Mice lacking all conventional MHC class II genes

1999 • 325 citations

γ chain required for naïve CD4+ T cell survival but not for antigen proliferation

2000 • 314 citations

Interleukin-7: master regulator of peripheral T-cell homeostasis?

2001 • 290 citations

Targeted Complementation of MHC Class II Deficiency by Intrathymic Delivery of Recombinant Adenoviruses

1997 • 204 citations

Organ‐specific Autoimmunity Induced by Lymphopenia

1996 • 194 citations

Autoimmune diseases and autoimmunity post-bone marrow transplantation

1998 • 188 citations

Impairment of immunological memory in the absence of MHC despite survival of memory T cells

2002 • 181 citations

Sensory Adaptation in Naive Peripheral CD4 T Cells

2001 • 163 citations

TCR and IL-7 Receptor Signals Can Operate Independently or Synergize to Promote Lymphopenia-Induced Expansion of Naive T Cells

2002 • 160 citations

Tetracycline-controllable Selection of CD4+ T Cells: Half-Life and Survival Signals in the Absence of Major Histocompatibility Complex Class II Molecules

2000 • 158 citations

Survival and Homeostatic Proliferation of Naive Peripheral CD4+ T Cells in the Absence of Self Peptide:MHC Complexes

2000 • 156 citations

CD4+ T cell survival is not directly linked to self-MHC–induced TCR signaling

2000 • 156 citations

Autologous Regulation of Naive T Cell Homeostasis Within the T Cell Compartment

2001 • 155 citations

Naïve cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?

1999 • 146 citations

Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes

2002 • 144 citations

Monoclonal antibody detection of a major self peptide. MHC class II complex.

1992 • 127 citations

Differential Survival of Naive CD4 and CD8 T Cells

2000 • 98 citations

Organ‐specific autoimmunity induced by adult thymectomy and cyclophosphamide‐induced lymphopenia

1995 • 84 citations

Cell division in the compartment of naive and memory T lymphocytes

1996 • 84 citations

Conversion of Naive T Cells to a Memory-Like Phenotype in Lymphopenic Hosts Is Not Related to a Homeostatic Mechanism That Fills the Peripheral Naive T Cell Pool

2002 • 81 citations

Naive CD4+ lymphocytes convert to anergic or memory-like cells in T cell-deprived recipients

2001 • 67 citations

Structurally interdependent and independent regions of allelic polymorphism in class II MHC molecules. Implications for Ia function and evolution.

1990 • 67 citations

Quantitative and Qualitative Adjustment of Thymic T Cell Production by Clonal Expansion of Premigrant Thymocytes

2002 • 26 citations

Gene Skews Patterns of Inheritance

1999 • 1 citations