Chromosomal instability in an oxygen-tolerant variant of Chinese hamster ovary cells

New Giemsa method for the differential staining of sister chromatids

1974 • 3,198 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

The aging process.

1981 • 1,871 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

Fractionation of DNA from mammalian cells by alkaline elution

1976 • 838 citations

Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol

1976 • 542 citations

The Relation of Free Radical Production to Hyperoxia

1986 • 382 citations

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

1981 • 275 citations

A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

1979 • 272 citations

The chromosomes of CHO, an aneuploid Chinese hamster cell line: G-band, C-band, and autoradiographic analyses

1973 • 249 citations

The Toxicology of Molecular Oxygen

1984 • 210 citations

Fluorometric quantitation of single-stranded DNA: A method applicable to the technique of alkaline elution

1982 • 150 citations

The Fragile X Chromosome

1983 • 144 citations

Mutagenicity and cytotoxicity of malonaldehyde in mammalian cells

1979 • 129 citations

Effect of oxygen tension on HeLa cell growth.

1960 • 111 citations

Report of the committee on chromosome markers

1976 • 108 citations

Genetic damage in CHO cells exposed to enzymically generated active oxygen species

1984 • 84 citations

Superoxide anion generated by potassium superoxide is cytotoxic and mutagenic to Chinese hamster ovary cells

1983 • 73 citations

Some characteristics of hyperoxia-adapted HeLa cells. A tissue culture model for cellular oxygen tolerance.

1985 • 70 citations

Measurement of sister chromatid exchanges at very low bromodeoxyuridine substitution levels using a monoclonal antibody in Chinese hamster ovary cells.

1985 • 69 citations

The biological activity of hydrogen peroxide

1986 • 66 citations

Genetic Consequences of Nucleotide Pool Imbalance

1986 • 65 citations

Density‐dependent effects of oxygen on the growth of mammalian fibroblasts in culture

1978 • 63 citations

Induction of chromosomal aberrations in cultured Chinese hamster cells in a superoxide-generating system

1984 • 58 citations

Characterization of an oxygen-tolerant cell line derived from Chinese hamster ovary

1985 • 52 citations

Effect of oxygen tension on chromosomal aberrations in Fanconi anaemia

1983 • 50 citations

Mechanisms for chromosomal aberrations in mammalian cells

1982 • 45 citations

DNA Lesions Induced by Ionizing Radiation

2007 • 40 citations

Chromosomal damage and mutations after exposure of chinese hamster cells to high concentrations of oxygen

1978 • 39 citations

Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells

1988 • 36 citations

Enhanced colony formation of human hemopoietic stem cells in reduced oxygen tension.

1986 • 31 citations

Characterization of oxygen-tolerant Chinese hamster ovary cells

1988 • 30 citations

The relationship between the induction of SCEs and mutations in Chinese hamster cells I. Experiments with hydrogen peroxide and caffeine

1986 • 26 citations

Molecular Mechanisms in Genetic Stability and Change: The Role of Deoxyribonucleotide Pool Balance

1985 • 25 citations

Chromosomal aberrations in v79 cells induced by superoxide radical generated by the hypoxanthinexanthine oxidase system

1984 • 24 citations

Detection of bromodeoxyuridine incorporation in mammalian chromosomes by a bromodeoxyuridine antibody

1986 • 24 citations

Production of sister chromatid exchanges by X-rays under aerobic and anaerobic conditions

2009 • 20 citations

Oxygen-induced cytogenetic instability in normal human lymphocytes

1986 • 16 citations

Oxygen dependence of sister-chromatid exchanges

1982 • 16 citations

Induction of 6-thioguanine-resistant mutants by hyperoxia and γ-irradiation: effect of compromising cellular antioxidant systems☆

1985 • 16 citations

Oxygen: Our major carcinogen?

1983 • 14 citations

Chromosomal rearrangements and gene expression in CHO Cells: Mapping of alleles for eight enzyme loci on CHO chromosomes Z3, Z4, Z5, and Z7

1984 • 14 citations

Purine modulation of thymidine activity in L1210 leukemia cells in vitro

1982 • 14 citations

Induction of Mutation and Chromosome Damage by Excess Bases and Nucleosides

1985 • 9 citations

BrdUrd-dependent sister-chromatid exchanges are increased at high oxygen tension

1985 • 2 citations

Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine.

1984 • 2 citations