Ionizing radiation induces heritable disruption of epithelial cell interactions

TGF-β signaling in tumor suppression and cancer progression

2001 • 2,235 citations

Putting tumours in context

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Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

1997 • 1,444 citations

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1992 • 1,047 citations

The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis

1999 • 916 citations

Regulation of Cadherin Adhesive Activity

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β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

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Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane

1989 • 700 citations

Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis

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Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial Cells

1997 • 633 citations

TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis

1998 • 630 citations

Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

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Transmission of chromosomal instability after plutonium α-particle irradiation

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Elimination of Metabolic Cooperation in Chinese Hamster Cells by a Tumor Promoter

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The cadherin-catenin adhesion system in signaling and cancer

2002 • 541 citations

Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells.

2000 • 537 citations

Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

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The cadherin-catenin adhesion system in signaling and cancer

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Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin.

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E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis

1997 • 341 citations

Stromal cells can contribute oncogenic signals

2001 • 326 citations

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

2001 • 305 citations

Phenotypic Reversion or Death of Cancer Cells by Altering Signaling Pathways in Three-Dimensional Contexts

2002 • 268 citations

Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic Instability

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Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation ¹

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Cancer as a dynamic developmental disorder.

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Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland.

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Incidence of Female Breast Cancer among Atomic Bomb Survivors, Hiroshima and Nagasaki, 1950-1980

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Mediation of Wound-Related Rous Sarcoma Virus Tumorigenesis by TGF-β

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Gap Junctions as Targets for Cancer Chemoprevention and Chemotherapy

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Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.

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Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communication.

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Radiation-induced Genomic Instability: Delayed Cytogenetic Aberrations and Apoptosis in Primary Human Bone Marrow Cells

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Cancer : a problem of developmental biology

1978 • 170 citations

Cancer mortality in a radiation-exposed cohort of Massachusetts tuberculosis patients.

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Dynamics of connexins, E-cadherin and α-catenin on cell membranes during gap junction formation

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Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells.

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1996 • 115 citations

Radiation-Induced Breast Cancer: Long-Term Follow-up of Radiation Therapy for Benign Breast Disease

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It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment.

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Efficient replacement of nonuniform objects in Web caches

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Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents.

1998 • 82 citations

Elimination of transformed cells by normal cells: a novel concept for the control of carcinogenesis.

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Dose– and time–response relationships for lethal mutations and chromosomal instability induced by ionizing radiation in an immortalized human keratinocyte cell line

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Modulation of Intercellular Communication during Radiation and Chemical Carcinogenesis

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Adverse effect of air pollution on respiratory health of primary school children in Taiwan.

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E-Cadherin (E-cad) expression in duct carcinoma in situ (DCIS) of the breast

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The potential influence of radiation-induced microenvironments in neoplastic progression.

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Ionizing Radiation Modulates Cell Surface Integrin Expression and Adhesion of COLO-320 Cells to Collagen and Fibronectin in Vitro

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Radiation-induced mutations in unirradiated DNA

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Effect of radiation on the expression of E-cadherin and α-catenin and invasive capacity in human lung cancer cell line in vitro

1998 • 28 citations

BioSig: an imaging bioinformatic system for studying phenomics

2002 • 22 citations

A new regularized approach for contour morphing

2002 • 12 citations

The aging lung: A challenging entity in respiratory medicine

2001 • 7 citations

In this issue

2001 • 2 citations