Induction of lambda 1-immunoglobulin is determined by a regulatory gene (r lambda 1) linked (or identical) to the structural (c lambda 1) gene.
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References (18)
Detection of specific sequences among DNA fragments separated by gel electrophoresis
1975 • 33,059 citations
Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.
1979 • 3,525 citations
Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.
1977 • 2,233 citations
A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines
1979 • 1,885 citations
A complete immunoglobulin gene is created by somatic recombination.
1978 • 610 citations
RECOMBINANT-INBRED STRAINS AN AID TO FINDING IDENTITY, LINKAGE, AND FUNCTION OF HISTOCOMPATIBILITY AND OTHER GENES
1971 • 595 citations
Analysis of the repertoire of anti‐(4‐hydroxy‐3‐nitro‐phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti‐idiotope antibodies
1979 • 254 citations
Deletions are associated with somatic rearrangement of immunoglobulin heavy chain genes
1980 • 159 citations
Organization of four mouse lambda light chain immunoglobulin genes.
1981 • 127 citations
Evolution of mouse immunoglobulin lambda genes.
1982 • 95 citations
Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.
1980 • 93 citations
Lambda chain expression at different stages of ontogeny in C57BL/6, BALB/c and SJL mice
1981 • 76 citations
On a regulatory gene controlling the expression of the murine lambda1 light chain.
1978 • 63 citations
The natural abundance of lambda2-light chains in inbred mice.
1978 • 61 citations
Sequences of immunoglobulin λ1 genes in a λ1 defective mouse strain
1982 • 40 citations
Unusual association of V, J and C regions in a mouse immunoglobulin λ chain
1982 • 32 citations
Monoclonal Antibodies to Murine Immunoglobulin Isotypes
1983 • 29 citations
Synthesis of λ1, λ2, and λ3 light chains by mouse spleen B cells
1982 • 20 citations