Characterization of an unusual and complex chromosome 21 rearrangement using somatic cell genetics and cloned DNA probes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES

1971 • 5,049 citations

A simple technique for demonstrating centromeric heterochromatin

1972 • 4,206 citations

Structure and variation of human ribosomal DNA: molecular analysis of cloned fragments

1981 • 235 citations

Precise localization of human beta-globin gene complex on chromosome 11.

1979 • 175 citations

Trisomie 21 et superoxyde dismutase-1 (IPO-A)

1976 • 175 citations

A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes

1985 • 162 citations

Down's syndrome

1974 • 134 citations

Genetic linkage map of human chromosome 21

1988 • 125 citations

Isolation of polymorphic DNA fragments from human chromosome 4

1987 • 100 citations

Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain

1976 • 98 citations

Cloned DNA probes regionally mapped to human Chromosome 21 and their use in determining the origin of nondisjunction

1985 • 93 citations

Synteny between glycinamide ribonucleotide synthetase and superoxide dismutase (soluble).

1977 • 83 citations

Regional localization of DNA sequences on chromosome 21 using somatic cell hybrids.

1986 • 82 citations

Familial Down syndrome due to t(10;21) translocation: evidence that the Down phenotype is related to trisomy of a specific segment of chromosome 21.

1975 • 77 citations

Chapter 2 Induction and Isolation of Auxotrophic Mutants in Mammalian Cells

1974 • 66 citations

Simultaneous identification of chromatid replication and of human chromosomes in metaphases of man-mouse somatic cell hybrids

1977 • 66 citations

Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated.

1985 • 61 citations

Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism: Characterization of Chinese hamster cell mutants defective in phosphoribosylpyrophosphate amidotransferase and phosphoribosylglycinamide synthetase and an examination of alternatives to the first step of purine biosynthesis

1977 • 46 citations

Isolation of polymorphic DNA segments from human chromosome 21

1985 • 38 citations

Human chromosome 21-encoded cDNA clones

1986 • 38 citations

Assignment of human phosphoribosylglycinamide synthetase locus to region 21q221

1984 • 35 citations

Characterization and Localization of the Human Genes for Ribosomal Ribonucleic Acid

1977 • 32 citations

Recent evolution of DNA sequence homology in the pericentromeric regions of human acrocentric chromosomes

1984 • 28 citations

The 724 family of DNA sequences is interspersed about the pericentromeric regions of human acrocentric chromosomes

1986 • 27 citations

Abstracts of workshop presentations (Part 13 of 13)

1985 • 26 citations

Ninth International Workshop on Human Gene Mapping

1986 • 14 citations

Regional assignment of six polymorphic DNA sequences on chromosome 21 by in situ hybridization to normal and rearranged chromosomes.

1988 • 12 citations