Synthetic Pentasaccharides Do Not Cause Platelet Activation by Antiheparin-Platelet Factor 4 Antibodies

A diagnostic test for heparin-induced thrombocytopenia

1986 • 706 citations

Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

1983 • 651 citations

Heparin-induced Thrombocytopenia: Towards Consensus

1998 • 555 citations

Recombinant Hirudin (Lepirudin) Provides Safe and Effective Anticoagulation in Patients With Heparin-Induced Thrombocytopenia

1999 • 502 citations

Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen.

1994 • 479 citations

Heparin-induced thrombocytopenia: laboratory studies

1988 • 423 citations

Heparin-induced thrombocytopenia: laboratory studies

1988 • 363 citations

Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia

1999 • 351 citations

Heparin-Associated Thrombocytopenia

1980 • 261 citations

Annotation

1995 • 233 citations

Biochemical and Pharmacological Properties of SANORG 34006, a Potent and Long-Acting Synthetic Pentasaccharide

1998 • 213 citations

Anticoagulation with Novastan^®(Argatroban) in Patients with Heparin-Induced Thrombocytopenia and Heparin-Induced Thrombocytopenia and Thrombosis Syndrome

1997 • 108 citations

BIOCHEMICAL AND PHARMACOLOGIC RATIONALE FOR THE DEVELOPMENT OF A SYNTHETIC HEPARIN PENTASACCHARIDE

1997 • 98 citations

SR 90107A/Org 31540, a Novel Anti‐Factor Xa Antithrombotic Agent

1997 • 93 citations

Efficacy of a Synthetic Pentasaccharide, a Pure Factor Xa Inhibitor, as an Antithrombotic Agent – A Pilot Study in the Setting of Coronary Angioplasty

1999 • 76 citations

Biochemical and Pharmacological Properties of SANORG 32701

1996 • 76 citations

Laboratory tests for heparin-induced thrombocytopenia: a multicenter study.

1999 • 64 citations

Methods of structural analysis

1983 • 59 citations

Effect of Glycoprotein IIb/IIIa Antagonists on the HIT Serum Induced Activation of Platelets

1997 • 49 citations

Antithrombotic Effects of Synthetic Pentasaccharide with High Affinity for Plasma Antithrombin III in Non-Human Primates

1993 • 44 citations

Antithrombotic potencies of heparins in relation to their antifactor Xa and antithrombin activities: an experimental study in two models of thrombosis in the rabbit

1990 • 36 citations

The biological basis of immune thrombocytopenia heparin-induced

1998 • 34 citations

Pentasaccharide and Orgaran® Arrest, whereas Heparin Delays Thrombus Formation in a Rat Arteriovenous Shunt

1993 • 26 citations

Comparison of a Synthetic Antithrombin III-binding Pentasaccharide and Standard Heparin as an Adjunct to Coronary Thrombolysis

1998 • 19 citations