Isolation and characterization of one soluble and two membrane-associated forms of phosphoinositide-specific phospholipase C from human platelets

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Protein a from Staphylococcus aureus. Its isolation by affinity chromatography and its use as an immunosorbent for isolation of immunoglobulins

1972 • 607 citations

Sequence similarity of phospholipase C with the non-catalytic region of src

1988 • 541 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Cloning and sequence of multiple forms of phospholipase C

1988 • 342 citations

Receptor-Coupled Activation of Phosphoinositide-Specific Phospholipase C by an N Protein

1986 • 324 citations

Purification of polyphosphoinositides by chromatography on immobilized neomycin.

1978 • 323 citations

Corticotropin-(1–24)-tetracosapeptide affects protein phosphorylation and polyphosphoinositide metabolism in rat brain

1981 • 287 citations

Molecular cloning and complete amino-acid sequence of form-I phosphoinositide-specific phospholipase C

1988 • 258 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

Bovine brain cytosol contains three immunologically distinct forms of inositolphospholipid-specific phospholipase C.

1987 • 233 citations

Inositol phospholipid-specific phospholipase C: complete cDNA and protein sequences and sequence homology to tyrosine kinase-related oncogene products.

1988 • 223 citations

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3

1985 • 175 citations

Purification and characterization of a phosphoinositide-specific phospholipase C from guinea pig uterus. Phosphorylation by protein kinase C in vivo.

1987 • 161 citations

Regulation of phosphoinositide breakdown by guanine nucleotides

1986 • 160 citations

Applications of Metal Buffers and Metal Indicators in Biochemistry

1956 • 158 citations

Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities

1988 • 155 citations

Purification of phosphoinositide‐specific phospholipase C from a particulate fraction of bovine brain

1987 • 124 citations

Phospholipase C associated with particulate fractions of bovine brain.

1987 • 111 citations

Isolation and characterization of two different forms of inositol phospholipid-specific phospholipase C from rat brain.

1988 • 108 citations

Regulation of membrane-associated and cytosolic phospholipase C activities in human platelets by guanosine triphosphate.

1986 • 98 citations

Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.

1988 • 90 citations

Characterization of multiple forms of phosphoinositide-specific phospholipase C purified from human platelets

1986 • 78 citations

Phospholipase C in rat liver plasma membranes

1986 • 53 citations

GTPγS-stimulated hydrolysis of phosphatidyinositol-4,5-bisphosphate by soluble phospholipase C from human platelets requires soluble GTP-binding protein

1988 • 35 citations

Partial Purification and Characterization of Membrane-Bound and Cytosolic Phosphatidylinositol-Specific Phospholipases C from Murine Thymocytes

1986 • 34 citations

Physical and Functional Association of Cytosolic Inositol-phospholipid-Specific Phospholipase C of Calf Thymocytes with a GTP-Binding Protein1

1987 • 34 citations

Studies on enzymes related to diacylglycerol production in activated platelets

1984 • 25 citations

In vivo distribution of phosphothioredoxin and thioredoxin in Escherichia coli

1978 • 24 citations

Properties of a Novel GTP-Binding Protein Which Is Associated with Soluble Phosphoinositides-Specific Phospholipase C1

1988 • 18 citations