Uptake and retention of morpholinyl anthracyclines by adriamycin-sensitive and-resistant P388 cells

Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.

1979 • 454 citations

All Patients with Acute Nonlymphocytic Leukemia May Have a Chromosomal Defect

1981 • 328 citations

Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia

1978 • 212 citations

Tissue distribution and disposition of daunomycin (NCS-82151) in mice: fluorometric and isotopic methods.

1970 • 146 citations

Intensely potent morpholinyl anthracyclines

1984 • 136 citations

Enhancement of vincristine- and adriamycin-induced cytotoxicity by verapamil in P388 leukemia and its sublines resistant to vincristine and adriamycin

1982 • 132 citations

Cellular transport of anthracyclines by passive diffusion

1985 • 102 citations

Molecular mechanisms of binding and single-strand scission of DNA by the antitumor antibiotics saframycins A and C

1982 • 100 citations

Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells

1984 • 86 citations

Cloning of human ovarian cancer cells in soft agar from malignant and peritoneal washings.

1980 • 73 citations

Dissociation of Antitumor Potency from Anthracycline Cardiotoxicity in a Doxorubicin Analog

1985 • 49 citations

Comparative cytotoxicities of various morpholinyl anthracyclines

1985 • 39 citations

Structure-activity relationship of anthracycline-induced genotoxicity in vitro.

1984 • 38 citations

The clinical evaluation of analogs ? III. Anthracyclines

1980 • 33 citations

Formation of DNA-adducts and induction of DNA-crosslinks and chromosomal aberrations by the new potent anthracycline antitumor antibiotics: morpholinodaunomycin, cyanomorpholinodaunomycin and cyanomorhpolinoadriamycin

1985 • 29 citations

Differences in daunomycin retention in sensitive and resistant P388 leukemic cells as determined by digitized video fluorescence microscopy.

1983 • 28 citations

Enhanced antitumor properties of 3'-(4-morpholinyl) and 3'-(4-methoxy-1-piperidinyl) derivatives of 3'-deaminodaunorubicin

1982 • 25 citations

3′-(3-cyano-4-morpholinyl)-3′-deaminoadriamycin: A new anthracycline with intense potency

1983 • 20 citations

Cellular pharmacology of 3'-(4-morpholinyl) and 3'-(4-methoxy-1-piperidinyl) derivatives of 3'-deaminodaunorubicin in human colon carcinoma cells in vitro.

1983 • 20 citations

Factors in Selection of New Anthracyclines

1982 • 8 citations