Hematopoietic Expression of Hoxb4 Is Regulated in Normal and Leukemic Stem Cells through Transcriptional Activation of the Hoxb4 Promoter by Upstream Stimulating Factor (Usf)-1 and Usf-2

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

1993 • 1,083 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene

1994 • 661 citations

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

1998 • 617 citations

Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.

1995 • 606 citations

Murine Developmental Control Genes

1990 • 594 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.

1994 • 529 citations

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences

1994 • 503 citations

Overexpression of HOXA10 in Murine Hematopoietic Cells Perturbs both Myeloid and Lymphoid Differentiation and Leads to Acute Myeloid Leukemia

1997 • 336 citations

Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells

1994 • 328 citations

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

1991 • 291 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila.

1983 • 282 citations

Initiation of Rhombomeric Hoxb4 Expression Requires Induction by Somites and a Retinoid Pathway

1998 • 275 citations

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

1997 • 272 citations

Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics

1996 • 252 citations

The Role of HOX Homeobox Genes in Normal and Leukemic Hematopoiesis

1996 • 239 citations

Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters.

1993 • 229 citations

Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII.

1994 • 218 citations

Overexpression of HOXB3 in Hematopoietic Cells Causes Defective Lymphoid Development and Progressive Myeloproliferation

1997 • 187 citations

Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice

1996 • 180 citations

Overlapping roles and asymmetrical cross-regulation of the USF proteins in mice

1998 • 161 citations

Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers.

1992 • 160 citations

Upstream Stimulatory Factor Binding to the E-box at −65 Is Required for Insulin Regulation of the Fatty Acid Synthase Promoter

1997 • 151 citations

Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene.

1988 • 146 citations

Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus

1996 • 133 citations

Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation

1994 • 128 citations

Microphthalmia-Associated Transcription Factor as a Regulator for Melanocyte-Specific Transcription of the Human Tyrosinase Gene

1994 • 103 citations

Thrombopoietin Promotes the Survival of Murine Hematopoietic Long-Term Reconstituting Cells: Comparison With the Effects of FLT3/FLK-2 Ligand and Interleukin-6

1998 • 89 citations

Thrombopoietin and the Hematopoietic Stem Cell

1998 • 89 citations

Abnormal Expression of Mouse Mast Cell Protease 5 Gene in Cultured Mast Cells Derived From Mutant mi/mi Mice

1997 • 87 citations

Modulation of homeobox gene expression alters the phenotype of human hematopoietic cell lines.

1992 • 81 citations

Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites.

1993 • 80 citations

Upstream Stimulatory Factor-2 (USF2) Activity Is Required for Glucose Stimulation of L-Pyruvate Kinase Promoter Activity in Single Living Islet β-Cells

1997 • 72 citations

Identification of homeobox genes expressed in human haemopoietic progenitor cells

1994 • 63 citations

Inhibition of retinoic acid-induced activation of 3' human HOXB genes by antisense oligonucleotides affects sequential activation of genes located upstream in the four HOX clusters.

1994 • 62 citations

Selective Utilization of Basic Helix-Loop-Helix–Leucine Zipper Proteins at the Immunoglobulin Heavy-Chain Enhancer

1997 • 50 citations

Pleckstrin Induces Cytoskeletal Reorganization via a Rac-dependent Pathway

1999 • 45 citations

Cloning and analysis of DNA-binding proteins by yeast one-hybrid and one-two-hybrid systems.

1996 • 36 citations

Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4.

1994 • 32 citations

Identification of homeobox-containing genes expressed in hematopoietic blast cells

1992 • 21 citations

Selective inhibition of normal murine myelopoiesis "in vitro" by a Hox 2.3 antisense oligodeoxynucleotide.

1992 • 18 citations

Regulation of the Nuclear Gene That Encodes the α-Subunit of the Mitochondrial F0F1-ATP Synthase Complex

1997 • 16 citations

Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells

1998 • 10 citations

Multiple Positive and Negative Regulatory Elements in the Promoter of the Mouse Homeobox Gene Hoxb-4

1994 • 5 citations