Neuroanatomical localization of the effects of (+)-HA966 on locomotor activity after cocaine injections to the nucleus accumbens of rats

A stereotaxic atlas of the rat brain

1967 • 4,710 citations

A stereotaxic atlas of the rat brain

1980 • 2,782 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Catecholamine innervation of the basal forebrain IV. Topography of the dopamine projection to the basal forebrain and neostriatum

1978 • 1,160 citations

The amygdalostriatal projection in the rat—an anatomical study by anterograde and retrograde tracing methods

1982 • 884 citations

The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde and retrograde-horseradish peroxidase study

1982 • 741 citations

Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801

1989 • 484 citations

The pharmacology and neural circuitry of sensitization to psychostimulants

1993 • 383 citations

Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.

1993 • 368 citations

The behavioral pharmacology of NMDA receptor antagonists

1990 • 331 citations

Excitatory amino acids and drugs of abuse: a role for N-methyl-d-aspartate receptors in drug tolerance, sensitization and physical dependence

1995 • 178 citations

The kappa-opioid receptor agonist U-69593 attenuates cocaine-induced behavioral sensitization in the rat

1993 • 152 citations

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative.

1990 • 135 citations

Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine

1991 • 131 citations

CNS Neurotransmitters and Neuromodulators: Glutamate

1995 • 100 citations

The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents

1993 • 94 citations

R‐(+)‐HA‐966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine

1991 • 75 citations

Excitatory amino acids and the actions of cocaine

1992 • 67 citations

Blockade of the locomotor stimulant effects of cocaine and methamphetamine by glutamate antagonists

1993 • 61 citations

Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal model of a poor debrisoquine metabolizer

1990 • 57 citations

Stress activation of mesocorticolimbic dopamine neurons: Effects of a glycine/NMDA receptor antagonist

1993 • 56 citations

Blockade of behavioral sensitization to methamphetamine by lesion of hippocampo-accumbal pathway

1991 • 40 citations

Behavioral studies with the glycine partial agonist (+)-HA966 on cocaine-induced locomotor activity and reinforcement

1995 • 33 citations

R-(+)-HA-966, an antagonist for the glycine/NMDA receptor, prevents locomotor sensitization to repeated cocaine exposures

1995 • 26 citations

Excitatory amino acid antagonists: Behavioral and biochemical approaches for the development of new central nervous system therapeutic agents

1989 • 22 citations