A Novel Method for SNP Detection Using a New Duplex-Specific Nuclease From Crab Hepatopancreas

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

1996 • 3,124 citations

Characterization of single-nucleotide polymorphisms in coding regions of human genes

1999 • 1,531 citations

Prospects for whole-genome linkage disequilibrium mapping of common disease genes

1999 • 1,453 citations

The essence of SNPs

1999 • 1,316 citations

SMART: a web-based tool for the study of genetically mobile domains

2000 • 1,298 citations

Accessing genetic variation: genotyping single nucleotide polymorphisms

2001 • 1,073 citations

CRYSTALLINE DESOXYRIBONUCLEASE

1950 • 690 citations

The use of a genetic map of biallelic markers in linkage studies

1997 • 499 citations

The use of single-nucleotide polymorphism maps in pharmacogenomics

2000 • 436 citations

Genetic manipulation of genomes with rare-cutting endonucleases

1996 • 385 citations

Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays

1999 • 381 citations

Amplification of cDNA ends based on template-switching effect and step- out PCR

1999 • 376 citations

Estimation of Population Parameters and Recombination Rates From Single Nucleotide Polymorphisms

2000 • 362 citations

Reading Bits of Genetic Information: Methods for Single-Nucleotide Polymorphism Analysis

1998 • 336 citations

CRYSTALLINE DESOXYRIBONUCLEASE

1950 • 185 citations

Why pharmacogenomics? Why now?

1998 • 120 citations

Enabling Technology:High-throughput genotyping assay approaches

2000 • 94 citations

Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53.

1995 • 85 citations

Pharmacogenetics

2001 • 81 citations

Bovine Pancreatic Deoxyribonuclease D

1974 • 68 citations

Biochemical characterization of Anabaena sp. strain PCC 7120 non‐specific nuclease NucA and its inhibitor NuiA

1998 • 50 citations

Kinetic Analysis of the Cleavage of Natural and Synthetic Substrates by the Serratia Nuclease

1996 • 48 citations

Single-Strand-Specific Nucleases

1995 • 47 citations

DNA recognition by structure-selective nucleases

1997 • 38 citations

Immobilized Nucleases

1993 • 35 citations

Cloning and characterization of a novel nuclease from shrimp hepatopancreas, and prediction of its active site

2000 • 17 citations

Potential nuclease-based strategies for HIV gene therapy

2000 • 16 citations

Purification, characterization and complete amino acid sequence of nuclease Cl from Cunninghamella echinulata var. echinulata

1998 • 14 citations

Shrimp hepatopancreatic deoxyribonuclease — purification and characterization as well as comparison with bovine pancreatic deoxyribonuclease

1990 • 14 citations

Protein structure and gene cloning of Syncephalastrum racemosum nuclease

1999 • 11 citations

Restriction Endonucleases and Their Uses

2003 • 5 citations

[Substrate specificity of Ca2+,Mg2+-dependent DNAase from sea urchin (Strongylocentrotus intermedius) embryos].

1981 • 2 citations