Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotype repertoire associated with aging.

Antitrinitrophenyl (TNP) Plaque Assay. Primary Response of Balb/c Mice to Soluble and Particulate Immunogen

1969 • 935 citations

Handbook of experimental immunology

1974 • 473 citations

Frequency of Pathological Proteins (M‐components) in 6,995 Sera from an Adult Population

1966 • 444 citations

Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice.

1976 • 239 citations

Loss of suppressor T cells in adult NZB/NZW mice.

1976 • 229 citations

Thymic Involution: Effect on T Cell Differentiation

1975 • 183 citations

Immunologic deficiencies in senescence. I. Characterization of intrinsic deficiencies.

1972 • 177 citations

Age, Thymic Involution, and Circulating Thymic Hormone Activity*

1978 • 162 citations

THE IMMUNOLOGIC THEORY OF AGING

1969 • 146 citations

Detection of anti‐idiotype reactive cells in the response to phosphorylcholine

1976 • 146 citations

Immune function in aged mice

1977 • 143 citations

Regulation of Immune Response by Autogenous Antibody against Receptor

1974 • 142 citations

Studies on the control of antibody synthesis. 3. Changes in heterogeneity of antibody affinity during the course of the immune response.

1973 • 132 citations

Inhibition of secondary anti‐hapten responses with the hapten conjugated to type 3 pneumococcal polysaccharide

1972 • 128 citations

Humoral immunity in aged mice. II. Increased suppressor T cell activity in immunologically deficient old mice.

1976 • 124 citations

The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice.

1975 • 117 citations

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. I. Occurrence in AKR/J and BALB/c mice of hapten-augmentable, anti-TNP plaque-forming cells and their accelerated appearance in recipients of immune spleen cells

1979 • 113 citations

Decline in Phytohemagglutinin Responsiveness of Spleen Cells from Aging Mice

1973 • 109 citations

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. II. Hapten-reversible inhibition of anti-TNP plaque-forming cells by immune serum as an assay for auto-anti-idiotypic antibody

1979 • 89 citations

Age-Related Changes in Cell-Mediated Immunity in BALB/C Mice

1975 • 82 citations

Immune function in aged mice IV. Loss of T cell and B cell function in thymus‐dependent antibody responses

1978 • 80 citations

Loss of immune competence with age may be due to auto-anti-idiotypic antibody regulation

1980 • 70 citations

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. III. Absence in nu/nu mice: evidence for T-cell dependence of the anti-idiotypic-antibody response.

1979 • 68 citations

Immune function in aged mice

1977 • 66 citations

Age related changes in the in vitro immune response: increased suppressor activity in immature and aged mice.

1980 • 65 citations

Patterned acquisition of the antibody repertoire: diversity of the hemagglutinin-specific B-cell repertoire in neonatal BALB/c mice.

1979 • 64 citations

Possible occurrence and meaning of lymphocytes bearing autoanti‐idiotypic receptors during the immune response

1978 • 59 citations

Thymosin and the immunopathology of aging.

1974 • 39 citations

Immunologicc activity of the aged.

1971 • 27 citations

Autoimmunity in aged mice. Occurrence of autoagglutinating factors in the blood of aged mice with medium and long life-spans.

1972 • 22 citations

Effect of age on ease of B-cell tolerance induction

1980 • 21 citations

B- and T-cell tolerance induction in young-adult and old mice

1976 • 20 citations

Studies on the resistance to tolerance induction against human IgG in DDD mice

1979 • 6 citations