Phenotypes of cells with cytoskeletal mutations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

1990 • 996 citations

Identification of γ-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans

1989 • 613 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans

1990 • 558 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

KAR3, a kinesin-related gene required for yeast nuclear fusion

1990 • 504 citations

The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs

1988 • 424 citations

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

1990 • 404 citations

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

1989 • 368 citations

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

1989 • 354 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans.

1989 • 292 citations

Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau

1989 • 281 citations

Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells.

1990 • 264 citations

Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity.

1989 • 253 citations

In pursuit of myosin function.

1989 • 252 citations

The functional importance of multiple actin isoforms

1990 • 239 citations

Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin

1990 • 229 citations

Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function.

1989 • 228 citations

Evidence that the Head of Kinesin Is Sufficient for Force Generation and Motility in Vitro

1990 • 225 citations

Two Drosophila beta tubulin isoforms are not functionally equivalent.

1990 • 212 citations

Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins.

1990 • 208 citations

The yeast MYO1 gene encoding a myosin-like protein required for cell division.

1987 • 199 citations

Intermediate filament dynamics

1990 • 184 citations

Functions of intermediate filaments

1989 • 178 citations

Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains.

1989 • 178 citations

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.

1990 • 173 citations

Identification and characterization of a gene encoding a kinesin-like protein in Drosophila

1990 • 172 citations

Actin-binding proteins

1990 • 164 citations

Villin induces microvilli growth and actin redistribution in transfected fibroblasts

1989 • 163 citations

Disruption of the actin cytoskeleton in yeast capping protein mutants

1990 • 162 citations

Genetic dissection of Drosophila myofibril formation: effects of actin and myosin heavy chain null alleles.

1989 • 156 citations

A Yeast Actin-Binding Protein Is Encoded by SAC6 , a Gene Found by Suppression of an Actin Mutation

1989 • 145 citations

Overexpression of the vimentin gene in transgenic mice inhibits normal lens cell differentiation.

1989 • 139 citations

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.

1990 • 137 citations

Molecular genetics of Drosophila alpha-actinin: mutant alleles disrupt Z disc integrity and muscle insertions.

1990 • 135 citations

The molecular cloning and identification of a gene product specifically required for nuclear movement in Aspergillus nidulans.

1990 • 135 citations

One motor, many tails: An expanding repertoire of force-generating enzymes

1990 • 134 citations

Alternative myosin hinge regions are utilized in a tissue-specific fashion that correlates with muscle contraction speed.

1990 • 115 citations

The minor myosin heavy chain, mhcA, of Caenorhabditis elegans is necessary for the initiation of thick filament assembly.

1989 • 114 citations

Multiple actin-based motor genes in Dictyostelium.

1989 • 110 citations

A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor.

1990 • 108 citations

A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.

1989 • 100 citations

The highly divergent beta-tubulins of Aspergillus nidulans are functionally interchangeable.

1989 • 96 citations

Wild-type and mutant actin genes in Caenorhabditis elegans

1989 • 86 citations

Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly

1990 • 80 citations

Molecular genetic dissection of myosin heavy chain function

1990 • 73 citations

Formation of reverse rigor chevrons by myosin heads

1989 • 68 citations

Myosin II heavy chain null mutant of Dictyostelium exhibits defective intracellular particle movement.

1990 • 68 citations

The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation.

1989 • 50 citations

Actin and actin‐binding proteins in yeast

1990 • 47 citations

Cytoskeletal ups and downs

1990 • 45 citations

Transgenic expression of the muscle-specific intermediate filament protein desmin in nonmuscle cells.

1989 • 42 citations

Hereditary disorders of the red cell membrane skeleton

1989 • 42 citations

Heterodimeric capping proteins constitute a highly conserved group of actin‐binding proteins

1990 • 20 citations

Biological roles of actin‐binding proteins in Dictyostelium discoideum examined using genetic techniques

1989 • 18 citations

Chapter 12 Expression and Function of Genetically Engineered Actin-Binding Proteins in Dictyostelium

1991 • 3 citations