Back to search

Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat

Data up to Jan 2025

Published1989
Citations36
References29

Total Citations Per Year

Abstract

References (29)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular Mechanisms in the Receptor Action of Benzodiazepines

1979 • 579 citations

Interaction of Convulsive Ligands with Benzodiazepine Receptors

1982 • 549 citations

A Selective Imidazobenzodiazepine Antagonist of Ethanol in the Rat

1986 • 545 citations

beta-Carbolines enhance shock-induced suppression of drinking in rats.

1983 • 217 citations

Photoaffinity Labeling of Benzodiazepine Receptor Proteins with the Partial Inverse Agonist [3H]Ro 15–4513: A Biochemical and Autoradiographic Study

1987 • 191 citations

Chloride-dependent enhancement by barbiturates of gamma-aminobutyric acid receptor binding

1982 • 183 citations

Diazepam enhancement of low affinity GABA binding to rat brain membranes

1982 • 166 citations

Is RO 15-4513 a specific alcohol antagonist?

1987 • 124 citations

Proconflict effect of benzodiazepine receptor inverse agonists and other inhibitors of GABA function

1984 • 109 citations

Effect of an imidazobenzodiazepine, Ro15-4513, on the incoordination and hypothermia produced by ethanol and pentobarbital

1987 • 107 citations

Does the reversal of the anticonflict effect of phenobarbital by β-CCE and FG 7142 indicate benzodiazepine receptor-mediated anxiogenic properties?

1982 • 105 citations

Stress and β-carbolines decrease the density of low affinity gaba binding sites

1984 • 100 citations

The benzodiazepine receptor inverse agonists FG 7142 and RO 15-4513 both reverse some of the behavioral effects of ethanol in a holeboard test

1987 • 90 citations

Enhancement by anesthetic and convulsant barbiturates of GABA binding to rat brain synaptosomal membranes

1981 • 58 citations

A study of the histamine H2‐receptor mediating relaxation of the parenchymal lung strip preparation of the guinea‐pig

1985 • 58 citations

Proconflict effect of GABA receptor complex antagonists

1986 • 54 citations

THE CONVULSANT ACTION OF HYDRAZIDES AND REGIONAL CHANGES IN CEREBRAL ?-AMINOBUTYRIC ACID AND PYRIDOXAL PHOSPHATE CONCENTRATIONS

1979 • 52 citations

The effects of compounds related to ?-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: Punished barpressing

1985 • 48 citations

Electrophysiological evidence that Ro 15-4513 is a benzodiazepine receptor inverse agonist

1987 • 41 citations

Anxiety-like subjective effect of ethanol antagonist Ro 15-4513 demonstrated in pentylenetetrazol discrimination

1987 • 38 citations

Modulation of GABA binding to rat brain membranes by alkyl β-carboline-3-carboxylate esters

1982 • 26 citations

Behavioral and biochemical evidence for a long-lasting decrease in GABAergic function elicited by chronic administration of FG 7142

1986 • 24 citations

Ethyl-β-carboline-3-carboxylate decreases [3H]GABA binding in membrane preparations of rat cerebral cortex

1983 • 23 citations

Antagonism of ethanol effects by Ro 15‐4513: An electrophysiological analysis

1989 • 23 citations

Ro 15-4513, like anxiogenic β-carbolines, increases dopamine metabolism in the prefrontal cortex of the rat

1988 • 20 citations

Enhancement of γ‐Aminobutyric Acid Binding by Quazepam, a Benzodiazepine Derivative with Preferential Affinity for Type I Benzodiazepine Receptors

1986 • 18 citations

Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896

1985 • 10 citations

Enhancement of γ‐Aminobutyric Acid Binding by the Anxiolytic β‐Carbolines ZK 93423 and ZK 91296

1987 • 8 citations

Cited By (0)

No citing papers found in database

Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has… (1989) – European Journal of Pharmacology | Metascience Observatory Explorer