CD8⁺ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum⁻ or helper peptides in priming for skin test reactivity to a P815AB‐related peptide

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells

1989 • 1,122 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1982 • 511 citations

Peptide synthesis. Part 2. Procedures for solid-phase synthesis using N^α-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and of acyl carrier protein 65–74 decapeptide

1981 • 396 citations

The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice.

1991 • 306 citations

The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones.

1989 • 304 citations

T helper type 1 development of naive CD4⁺ T cells requires the coordinate action of interleukin‐12 and interferon‐γ and is inhibited by transforming growth factor‐β

1994 • 288 citations

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

1978 • 268 citations

Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.

1983 • 251 citations

Role of dendritic cells in the priming of CD4+ T lymphocytes to peptide antigen in vivo.

1993 • 164 citations

Toward a Genetic Analysis of Tumor Rejection Antigens

1992 • 151 citations

Induction of CD8⁺ cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells

1993 • 138 citations

Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination.

1992 • 135 citations

Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. I. Rejection by syngeneic mice.

1980 • 129 citations

Cancer vaccines

1993 • 129 citations

Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen.

1979 • 122 citations

Mouse tumor rejection antigens P815A and P815B : Two epitopes carried by a single peptide

1992 • 99 citations

Identification of tumour rejection antigens recognized by T lymphocytes.

1992 • 72 citations

Tumor-rejection antigens recognized by T lymphocytes

1993 • 45 citations

Chemical xenogenization of experimental tumors

1987 • 43 citations

Skin test to assess virus-specific cytotoxic T-cell activity.

1992 • 43 citations

Induction of a cytotoxic T cell response by co‐injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): Further enhancement by pre‐injection of IFA alone

1994 • 39 citations

Use of a skin test assay to determine tumor‐specific CD8⁺ T cell reactivity

1994 • 38 citations

Immunity and metastasis: in situ activation of protective T cells by virus modified cancer vaccines.

1992 • 25 citations

Alteration of immunogenicity of xenogenized tumor cells in syngeneic rats by the immune responses to virus-associated antigens produced on immunizing cells.

1983 • 25 citations

Delayed‐type hypersensitivity to tumor antigens co‐expressed with immunogenic determinants induced by xenogenization

1989 • 23 citations

Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine tumor.

1995 • 18 citations

Induction of tumor suppression and delayed-type footpad reaction by transfer of lymphocytes sensitized to a xenogenized tumor variant

1988 • 16 citations

Enhancement of IgG production elicited in mice by treatment with anti‐CD8 antibody

1991 • 15 citations

Transfection of interferon-gamma gene in animal tumors--a model for local cytokine production and tumor immunity.

1992 • 14 citations

T‐cell subsets, IFN‐γ production and efferent specificity in anti‐parental tumor immunity induced by mouse sensitization with xenogenized variant cells

1990 • 5 citations