Chemical xenogenization of experimental tumors

DNA Methylation and Gene Function

1980 • 2,069 citations

Protides of Biological Fluids

1971 • 471 citations

Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies

1985 • 301 citations

Immunologic Mechanisms in UV Radiation Carcinogenesis

1981 • 295 citations

Teratomas and differentiation

1975 • 252 citations

VIRAL ONCOLYSIS: INCREASED IMMUNOGENICITY OF HOST CELL ANTIGEN ASSOCIATED WITH INFLUENZA VIRUS

1967 • 234 citations

Methylation and gene control

1982 • 210 citations

Antigenic Tumor Cell Variants Obtained with Mutagens

1983 • 166 citations

Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. II. T lymphocyte-mediated cytolysis.

1980 • 162 citations

Rejection by syngeneic mice of cell variants obtained by mutagenesis of a malignant teratocarcinoma cell line.

1977 • 147 citations

Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis.

1982 • 143 citations

Tumour specific immunogenicity of methylcholanthrene-induced sarcoma cells after incubation in neuraminidase.

1969 • 133 citations

Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. I. Rejection by syngeneic mice.

1980 • 129 citations

Possible epigenetic mechanisms of tumor progression: Induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment

1984 • 125 citations

On the genesis and regulation of cellular heterogeneity in malignant tumors.

1982 • 122 citations

Tumour inhibitory triazenes: Structural requirements for an active metabolite

1976 • 122 citations

IMMUNOLOGICAL ALTERNATION OF LEUKEMIC CELLS In Vivo AFTER TREATMENT WITH AN ANTITUMOR DRUG

1970 • 121 citations

Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.

1984 • 110 citations

Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. I. Parameters for optimal therapeutic effects

1986 • 109 citations

Neoplastic Development 2

1975 • 104 citations

Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. III. Clonal analysis of the syngeneic cytolytic T lymphocyte response

1982 • 89 citations

Effective tumor immunization induced by cells of elevated membrane-lipid microviscosity.

1979 • 89 citations

Teratocarcinoma cell variants rejected by syngeneic mice: protection of mice immunized with these variants against other variants and against the original malignant cell line.

1978 • 88 citations

On a possible epigenetic mechanism(s) of tumor cell heterogeneity

1983 • 87 citations

Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.

1984 • 85 citations

Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.

1983 • 83 citations

Modification of tumor regression by immunologic means.

1969 • 79 citations

Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis.

1983 • 79 citations

Immunogenicity of Leukemia L1210 Cells After Neuraminidase Treatment<xref ref-type="fn" rid="FN1">2</xref>

1972 • 79 citations

Viral Xenogenization of Intact Tumor Cells

1979 • 71 citations

Antigenic changes of L1210 leukemia in mice treated with 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide.

1972 • 71 citations

Antigenicity of L1210 leukemic sublines induced by drugs.

1972 • 66 citations

Virus Augmentation of The Antigenicity of Tumor Cell

1979 • 64 citations

Enhanced Expression of Class I Major Histocompatibility Complex Gene (&lt;italic&gt;D&lt;/italic&gt;&lt;sup&gt;&lt;italic&gt;k&lt;/italic&gt;&lt;/sup&gt;) Products on Immunogenic Variants of a Spontaneous Murine Carcinoma&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1985 • 63 citations

Induction of immune responsiveness in a genetically low-responsive tumor-host combination by chemical modification of the immunogen

1976 • 56 citations

Tumor cell variants obtained by mutagenesis of a Lewis lung carcinoma cell line: immune rejection by syngeneic mice.

1979 • 54 citations

Antigenic Changes of L5178Y Lymphoma After Treatment With 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide In Vivo 2

1976 • 52 citations

Drug-Mediated Antigenic Changes in Murine Leukemia Cells: Antagonistic Effects of Quinacrine, an Antimutagenic Compound23

1980 • 51 citations

Increase in H-2 antigen expression and immunogenicity of BL6 melanoma cells treated with N-methyl-N'-nitronitrosoguanidine.

1985 • 49 citations

Cellular immune response to a drug-treated L5178Y lymphoma subline

1974 • 49 citations

Tumor Associated Antigens and Their Specific Immune Response

1980 • 43 citations

Drug-mediated immunogenic changes of virus-induced leukemia in vivo.

1976 • 41 citations

IN VITRO GENERATION OF PRIMARY CYTOTOXIC LYMPHOCYTES AGAINST L5178Y LEUKEMIA ANTIGENICALLY ALTERED BY 5-(3,3'-DIMETHYL-l-TRIAZENO)-IMIDAZOLE-4-CARBOXAMIDE IN VIVO

1979 • 41 citations

Active specific immunotherapy of minimal residual tumor: Excision plus neuraminidase‐treated tumor cells

1974 • 41 citations

In vitro generation of a highly immunogenic subline of L1210 leukemia following exposure to 5-(3,3'-dimethyl-1-triazeno)imidazole-4-carboxamide.

1981 • 40 citations

Drug-mediated increase of tumor immunogenicity in vivo for a new approach to experimental cancer immunotherapy.

1981 • 38 citations

Effect of 5-azacytidine on DNA methylation and the malignant properties of B16 melanoma cells.

1985 • 35 citations

Radioresistant inhibition of lymphoma growth in congenitally athymic (nude) mice.

1977 • 32 citations

Immunity to lymphoid tumors in syngeneic mice by immunization with mitomycin C-treated cells.

1977 • 32 citations

Neuraminidase Induced Loss in the Transplantability of Murine Leukaemia L 1210, Induction of Immunoprotection and the Transfer of Induced Immunity to Normal DBA/2 Mice by Serum and Peritoneal Cells

1973 • 32 citations

Brief Communication: Increased Immunogenicity of Two Lymphoma Lines After Drug Treatment of Athymic (Nude) Mice

1975 • 30 citations

Drug-Induced Immunogenic Changes of Murine Leukemia Cells: Dissociation of Onset of Resistance and Emergence of Novel Immunogenicity&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1983 • 27 citations

Intracerebral Adoptive Immunotherapy of a Murine Lymphoma Antigenically Altered by Drug Treatment In Vivo&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;, &lt;xref ref-type="fn" rid="fn3"&gt;3&lt;/xref&gt;

1982 • 26 citations

Induction of highly immunogenic variants of Lewis lung carcinoma tumor by ultraviolet irradiation.

1985 • 26 citations

Artificial Heterogenization of Tumours by means of Herpes Simplex and Polyoma Viruses

1964 • 25 citations

GROWTH AND REJECTION PATTERNS OF MURINE LYMPHOMA CELLS ANTIGENICALLY ALTERED FOLLOWING DRUG TREATMENT IN VIVO

1978 • 25 citations

Humoral response against murine lymphoma cells xenogenized by drug treatmentin vivo

1985 • 25 citations

Immunogenic changes of murine lymphoma cells following in vitro treatment with aryl-triazene derivatives

1984 • 24 citations

Tum variants: immunogenic variants obtained by mutagen treatment of tumor cells

1985 • 22 citations

Long-term depression of two primary immune responses induced by a single dose of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC)

1978 • 20 citations

Immunosensitivity and histocompatibility antigens in drug-altered leukemic cells.

1976 • 19 citations

Systemic adoptive immunotherapy of a highly immunogenic murine lymphoma growing in the brain

1983 • 19 citations

Adoptive immunotherapy of intracerebral murine lymphomas: Role of different lymphoid populations

1985 • 18 citations

Chemical xenogenization of murine lymphoma cells with triazene derivatives: Immunotoxicological studies

1984 • 18 citations

Immunity to Lymphoid Tumors Induced in Syngeneic Mice by Immunization with Mitomycin C-Treated Cells

1977 • 18 citations

Inhibition of murine lymphoma growth by adoptive transfer of lymphocytes sensitized to a xenogenized tumor variant

1987 • 17 citations

Chemical xenogenization of tumor cells

1985 • 17 citations

Antigenic changes of a murine lymphoma by in vivo treatment with triazene derivatives

1981 • 15 citations

Secondary Cytotoxic Response In Vitro Against Moloney Lymphoma Cells Antigenically Altered by Drug Treatment In Vivo

1978 • 15 citations

Induction of tumor cell rejection in the low responsive YAC-lymphoma strain A host combination by immunization with somatic cell hybrids

1979 • 15 citations

Effects of mutagens on the immunogenicity of tumor cells: comparison of cell surface changes induced by 5-azacytidine and N-methyl-N'-nitro-N-nitrosoguanidine.

1986 • 14 citations

Increased immunogenicity of L1210 leukemia following short-term exposure to 5(3,3?-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) in vivo or in vitro

1979 • 14 citations

Dna methylating activity in murine lymphoma cells xenogenized by triazene derivatives

1987 • 14 citations

Metastatic phenotype of human prostate tumor cells in athymic nude mice: Alteration by exposure to ethyl methanesulfonate and ?reversion? by 5-azacytidine

1986 • 13 citations

Increased immunosensitivity in nitrogen mastard-resistant Yoshida sarcoma.

1973 • 12 citations

Induction of non-transplantable mutant clones from an ascites tumor.

1969 • 12 citations

Appearance of Strong Transplantation Antigens in Non-Immunogenic Lymphoma Following Drug-Treatment In Vivo

1980 • 11 citations

Increased immunogenicity of murine lymphatic tumors by pyrazole-4-carboxamide, 3(or 5)-amino (NSC-1402; PCA).

1973 • 11 citations

Immunogenic cell variants of a mouse teratocarcinoma confer a protection against the original non-immunogenic transplantable tumor

1981 • 10 citations

Monoclonal antibodies to the L1210 murine leukemia cell line and to a drug-altered subline.

1985 • 8 citations

Expression of normal histocompatibility antigens in murine lymphomas treated with 5-(3,3′-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) in vivo

1981 • 7 citations

Influence of glucan on experimental infections in mice

1980 • 6 citations

Tumor-cell Variants With Increased Immunogenicity Obtained By Mutagen Treatment

1985 • 6 citations

Increased frequency of immunogenic variants obtained by repeated mutagen treatment of mouse mastocytoma P815

1983 • 6 citations

Antigenic properties of lymphoma sublines derived from a drug-treated immunogenic L5178Y leukemia.

1978 • 6 citations

Tumour cell variants with increased immunogenicity obtained by mutagen treatment.

1985 • 5 citations

DNA methylating activity in murine lymphoma cells treated with xenogenizing chemicals.

1987 • 2 citations

Immunogenicity of viable tumor cells

1986 • 1 citations