Intracellular interleukin 6 mediates platelet-derived growth factor-induced proliferation of nontransformed cells.

The biology of interleukin-6

1989 • 1,964 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

Interleukin-6 and Its Receptor: A Paradigm for Cytokines

1992 • 889 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6.

1990 • 500 citations

Inhibition of Cellular Proliferation by Antisense Oligodeoxynucleotides to PCNA Cyclin

1988 • 425 citations

Cell cycle regulation of the human cdc2 gene.

1992 • 396 citations

Proliferating or interleukin 1-activated human vascular smooth muscle cells secrete copious interleukin 6.

1990 • 364 citations

Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors.

1988 • 235 citations

Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression.

1993 • 233 citations

Transformation by v- sis Occurs by an Internal Autoactivation Mechanism

1989 • 171 citations

Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines.

1991 • 123 citations

Interleukin 1: The patterns of translation and intracellular distribution support alternative secretory mechanisms

1992 • 92 citations

Mechanism of Autocrine Stimulation in Hematopoietic Cells Producing Interleukin-3 after Retrovirus-Mediated Gene Transfer

1989 • 62 citations

Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers.

1991 • 49 citations

Interleukin-6 functions as an intracellular growth factor in hairy cell leukemia in vitro.

1993 • 45 citations

Manidipine regulates the transcription of cytokine genes.

1992 • 44 citations

Interleukin-6 (IL-6) is an intermediate in IL-1-induced proliferation of leukemic human megakaryoblasts

1990 • 38 citations

Cell cultures from cryopreserved human lung tissue

1992 • 22 citations