Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Atherosclerosis and the Arterial Smooth Muscle Cell

1973 • 1,503 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

PLATELET-DERIVED GROWTH FACTOR

1989 • 967 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

1988 • 481 citations

Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol

1984 • 393 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction.

1988 • 215 citations

Effect of Phospholipase C-γ Overexpression on PDGF-induced Second Messengers and Mitogenesis

1990 • 170 citations

Different effects of platelet-derived growth factor isoforms on rat vascular smooth muscle cells.

1990 • 155 citations

Ca2+-channel blockers inhibit the action of recombinant platelet-derived growth factor in vascular smooth muscle cells.

1989 • 138 citations

Interleukin 3 stimulates proliferation via protein kinase C activation without increasing inositol lipid turnover.

1988 • 108 citations

Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.

1987 • 84 citations

Regulation of the low density lipoprotein receptor and hydroxymethylglutaryl coenzyme A reductase genes by protein kinase C and a putative negative regulatory protein.

1989 • 70 citations

Mechanism of the Growth-related Activation of the Low Density Lipoprotein Receptor Pathway

1989 • 56 citations

[62] Fast blots: Immobilization of DNA and RNA from cells

1987 • 53 citations

Association of platelet-derived growth factor-induced protein with nuclear material

1983 • 42 citations

Multiple modes of protein kinase C regulation and their significance in signalling

1988 • 24 citations

Comparison of platelet-derived growth factor prepared from release products of fresh platelets and from outdated platelet concentrates

1983 • 19 citations