Time-dependent changes in H1 content, H1 turnover, DNA elongation, and the survival of cells blocked in early S phase by hydroxyurea, aphidicolin, or 5-fluorodeoxyuridine

Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle.

1983 • 452 citations

Heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels

1969 • 393 citations

The anatomy of the T5 bacteriophage DNA molecule

1966 • 373 citations

Enhancement of Methotrexate Resistance and Dihydrofolate Reductase Gene Amplification by Treatment of Mouse 3T6 Cells with Hydroxyurea

1983 • 191 citations

Gene amplification in a single cell cycle in Chinese hamster ovary cells.

1984 • 190 citations

Isoleucine-mediated regulation of genome repliction in various mammalian cell lines.

1971 • 188 citations

Cell heterogeneity during the cell cycle

1982 • 157 citations

Correlated Measurements of DNA, RNA, and Protein in Individual Cells by Flow Cytometry

1985 • 153 citations

REGULATION OF INITIATION OF DNA SYNTHESIS IN CHINESE HAMSTER CELLS

1970 • 149 citations

Correlation between cell enlargement and nucleic acid and protein content of hela cells in unbalanced growth produced by inhibitors of DNA synthesis

1967 • 138 citations

Inhibition of DNA replication coordinately reduces cellular levels of core and H1 histone mRNAs: requirement for protein synthesis

1984 • 123 citations

Cell Growth and Division

1969 • 122 citations

Rapid reversible changes in the rate of histone gene transcription and histone mRNA levels in mouse myeloma cells.

1984 • 100 citations

Age responses of cultured mammalian cells to cytotoxic drugs.

1970 • 88 citations

Hydroxyurea does not prevent synchronized G1 chinese hamster cells from entering the DNA synthetic period

1976 • 87 citations

CELLULAR AND NUCLEAR VOLUME DURING THE CELL CYCLE OF NHIK 3025 CELLS

1978 • 71 citations

Hydroxyurea-Induced Accumulation of Short Fragments During Polyoma DNA Replication I. Characterization of Fragments

1973 • 68 citations

Growth inhibition of a human tumor cell strain by 5-fluoro-2-deoxyuridine: time parameters for subsequent reversal by thymidine.

1959 • 68 citations

Three‐color fluorescence measurements on single cells excited at three laser wavelengths

1982 • 65 citations

The ratio of RNA to total nucleic acid content as a quantitative measure of unbalanced cell growth

1982 • 61 citations

Normal and perturbed Chinese hamster ovary cells: correlation of DNA, RNA, and protein content by flow cytometry.

1985 • 55 citations

CELL VOLUME GROWTH AFTER CELL CYCLE BLOCK WITH CHEMOTHERAPEUTIC AGENTS

1976 • 49 citations

Syntheses and modulations in the chromatin contents of histones H1.degree. and H1 during G1 and S phases in Chinese hamster cells

1982 • 47 citations

Cell cycle regulation of human histone H1 mRNA.

1984 • 45 citations

Effect of inhibition of DNA synthesis on histone synthesis and deposition

1978 • 41 citations

The metabolism of histone fractions

1974 • 39 citations

Aphidicolin inhibits the synthesis and joining of short DNA fragments but not the union of 10-kilobase DNA replication intermediates.

1983 • 37 citations

The effects of 5-fluorodeoxycytidine, 5-fluorodeoxyuridine, and related compounds on transplanted mouse leukemias.

1959 • 37 citations

Zinc-induced resistance to alkylating agent toxicity.

1982 • 28 citations

Effects of X-Irradiation on DNA Precursor Metabolism and Deoxyribonucleoside Triphosphate Pools in Chinese Hamster Cells

1974 • 28 citations

Arrest of Chain Growth of Replicon‐Sized Intermediates by Aphidicolin During Rat Fibroblast Cell Chromosome Replication

1982 • 27 citations

Requirement of protein synthesis for the coupling of histone mRNA levels and DNA replication

1984 • 26 citations

Inhibitors of DNA synthesis induce sister chromatid exchanges at the early S phase of the cell cycle

1984 • 25 citations

The effect of hydroxyurea on the mechanism of DNA synthesis in the yeast Saccharomyces cerevisiae

1980 • 24 citations

Properties of various rotors used for zone centrifugation

1973 • 23 citations

Replication of DNA in mammalian chromosomes

1977 • 21 citations

A procedure for the rapid lysis of mammalian cells prior to alkaline sucrose density gradient centrifugation

1975 • 20 citations

Unbalanced growth and cell death in HeLa S3 cultures treated with DNA synthesis inhibitors

1981 • 19 citations

Composition and synthesis during G1 and S phase of a high mobility group-E/G component from Chinese hamster ovary cells

1983 • 17 citations

Chromatin structural changes in synchronized cells blocked in early S phase by sequential use of isoleucine deprivation and hydroxyurea blockade

1983 • 15 citations

Survival of CHO cells that replicated DNA in the presence of hydroxyurea*1

1977 • 15 citations

Changes in histone H1 content and chromatin structure of cells blocked in early S phase by 5-fluorodeoxyuridine and aphidicolin

1984 • 15 citations

PH stepwise alkaline elution of DNA replication intermediates during S phase

1981 • 9 citations

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