Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

1979 • 727 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum.

1977 • 587 citations

Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?

1983 • 471 citations

A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions.

1983 • 368 citations

Recent progress in hormone research

1990 • 359 citations

Subcellular localization of the superoxide-forming enzyme in human neutrophils.

1979 • 268 citations

Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium

1983 • 217 citations

[12] Isolation of human platelets and platelet surface membranes

1974 • 213 citations

Calcium and cell function

1983 • 207 citations

Direct demonstration of increased intracellular concentration of free calcium in rabbit and human neutrophils following stimulation by chemotactic factor

1983 • 199 citations

Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.

1985 • 196 citations

Phospholipid Turnover in Hormone Action

1984 • 178 citations

Preparation, Properties, and Specific Recombination of αβ-Globin Subunits

1964 • 166 citations

Polypeptide hormone regulation of gene expression. Thyrotropin-releasing hormone rapidly stimulates both transcription of the prolactin gene and the phosphorylation of a specific nuclear protein.

1983 • 164 citations

Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling.

1975 • 123 citations

Ultrastructural Demonstration of Calcium Loss from Local Regions of the Plasma Membrane of Surface-Stimulated Human Granulocytes

1979 • 118 citations

Phospholipid-sensitive Ca2+-dependent protein kinase and its substrates in human neutrophils

1983 • 112 citations

Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester

1984 • 109 citations

Calcium movement and membrane potential changes in the early phase of neutrophil activation by phorbol myristate acetate: a study with ion-selective electrodes.

1982 • 97 citations

A Role of Membranes in the Activation of a New Multifunctional Protein Kinase System

1979 • 86 citations

Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine.

1981 • 82 citations

Platelet Ca2+-activated, phospholipid-dependent protein kinase: Evidence for proteolytic activation of the enzyme in cells treated with phospholipase C

1984 • 74 citations

Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase

1985 • 70 citations

Subcellular distribution of phospholipid-sensitive calcium-dependent protein kinase in guinea pig heart, spleen and cerebral cortex, and inhibition of the enzyme by Triton X-100

1982 • 50 citations

Effect of the chemotactic factor formyl methionyl‐leucyl‐phenylalanine and cytochalasin B on the cellular levels of calcium in rabbit neutrophils

1979 • 36 citations

Ca2+-dependent neutral proteinase from human erythrocytes: activation by Ca2+ ions and substrate and regulation by the endogenous inhibitor.

1984 • 28 citations

Phospholipid-sensitive calcium-dependent protein kinase and its endogenous substrate proteins in rat pancreatic acinar cells

1983 • 21 citations

Determination of Ca2+- and phospholipid-dependent protein kinase in rat liver membranes

1983 • 11 citations