Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

A non-disruptive technique for loading calcium buffers and indicators into cells

1981 • 1,121 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

1979 • 556 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1978 • 355 citations

Calmodulin. Development and application of a sensitive radioimmunoassay.

1979 • 350 citations

Synergistic functions of phorbol ester and calcium in serotonin release from human platelets

1983 • 335 citations

Chemoattractants stimulate degradation of methylated phospholipids and release of arachidonic acid in rabbit leukocytes.

1979 • 279 citations

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters.

1982 • 271 citations

Receptor-mediated uptake and degradation of 125I-chemotactic peptide by human neutrophils.

1979 • 243 citations

Visualization of membrane bound cations by a fluorescent technique

1971 • 224 citations

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.

1984 • 221 citations

Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium

1983 • 217 citations

Inhibition of epidermal growth factor binding to surface receptors by tumor promotors

1979 • 206 citations

Direct demonstration of increased intracellular concentration of free calcium in rabbit and human neutrophils following stimulation by chemotactic factor

1983 • 199 citations

Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils

1983 • 188 citations

Chemotactic peptide receptor modulation in polymorphonuclear leukocytes.

1980 • 183 citations

Phorbol myristate acetate-induced release of granule enzymes from human neutrophils: Inhibition by the calcium antagonist, 8-(N,N-diethylamino)-octyl 3,4,5-trimethoxybenzoate hydrochloride

1979 • 169 citations

Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor

1979 • 154 citations

Endogenous protein phosphorylation by resting and activated human neutrophils

1983 • 143 citations

Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline.

1979 • 128 citations

Human neutrophils contain an intracellular pool of putative receptors for the chemoattractant N-formyl-methionyl-leucyl-phenylalanine

1983 • 118 citations

Tumour promoter uncouples β-adrenergic receptor from adenyl cyclase in mouse epidermis

1980 • 114 citations

Phospholipid-sensitive Ca2+-dependent protein kinase and its substrates in human neutrophils

1983 • 112 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. I. Use of chlorotetracycline as fluorescent probe.

1978 • 108 citations

Phorbol ester stimulation of Na influx and Na-K pump activity in swiss 3T3 cells

1981 • 106 citations

The formylpeptide chemotactic receptor on rabbit peritoneal neutrophils. I. Evidence for two binding sites with different affinities.

1982 • 82 citations

Chemotactic Factor-Induced Generation of Superoxide Radicals by Human Neutrophils: Evidence for the Role of Sodium

1979 • 74 citations

Relation of human neutrophil phorbol ester receptor occupancy and NADPH- oxidase activity

1982 • 69 citations

Receptor-mediated activation of a phospholipase A2 in rabbit neutrophil plasma membrane.

1984 • 66 citations

Effect of chemotactic factors on calcium levels of rabbit neutrophils

1979 • 65 citations

Cellular regulatory role of leukotriene B₄: Its effects on cation homeostasis in rabbit neutrophils

1981 • 61 citations

Transmembrane potential changes associated with superoxide release from human granulocytes

1981 • 59 citations

Response of adenosine cyclic 3',5'-monophosphate level in rabbit neutrophils to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine.

1979 • 53 citations

Endogenous substrates for cyclic AMP-dependent and calcium-dependent protein phosphorylation in rabbit peritoneal neutrophils

1983 • 44 citations

Activation of the rabbit polymorphonuclear leukocyte membrane "Na+, K+"-ATPase by chemotactic factor

1978 • 37 citations

FMLP-induced enzyme release from neutrophils: a role for intracellular calcium

1983 • 36 citations

Binding of the chemotactic synthetic peptide [³H]formyl—nor‐leu—leu—phe to plasma membrane of rabbit neutrophils

1978 • 35 citations

Calcium ion-dependent adenosine triphosphatase activity and plasma-membrane phosphorylation in the human neutrophil

1979 • 34 citations

Mechanism of action of leukotriene B₄: Intracellular calcium redistribution in rabbit neutrophils

1984 • 33 citations

Calcium in Biological Systems

1985 • 30 citations

Increased fluorescence polarization of 1,6‐diphenyl‐1,3,5‐hexatriene in the phorbol myristate acetate‐stimulated plasma membrane of human neutrophils

1982 • 29 citations

Phosphorylation of myosin light chain in intact pig leukocytes stimulated by phorbol 12-myristate 13-acetate

1984 • 17 citations

Intracellular or extracellular calcium can be used to trigger C5a-stimulated enzyme secretion from rabbit neutrophils

1983 • 7 citations