Intraventricular injections of drugs which inhibit phospholipase A2 suppress fever in rabbits.

Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

1980 • 925 citations

The importance of phospholipase-A2 in prostaglandin biosynthesis

1976 • 647 citations

Effects on body temperature of prostaglandins of the A, E and F series on injection into the third ventricle of unanaesthetized cats and rabbits

1971 • 358 citations

EIGHTH GADDUM MEMORIAL LECTURE UNIVERSITY OF LONDON INSTITUTE OF EDUCATION DECEMBER 1980: BIOLOGICAL IMPORTANCE OF PROSTACYCLIN

1982 • 276 citations

Molecular basis of fever in humans

1982 • 252 citations

Selective inhibition by mepacrine of the release of “rabbit aorta contracting substance” evoked by the administration of bradykinin

1972 • 249 citations

The Role of Prostaglandins in the Central Nervous System

1979 • 241 citations

Changes in body temperature after administration of acetylcholine, histamine, morphine, prostaglandins and related agents

1980 • 167 citations

Effect of pyrogen and antipyretics on prostaglandin activity in cisternal c.s.f. of unanaesthetized cats

1973 • 166 citations

Endogenous inhibitor of prostaglandin synthetase

1977 • 149 citations

Ability of Human Leukocytic Pyrogen to Stimulate Brain Prostaglandin Synthesis In Vitro

1982 • 135 citations

Prostaglandin E levels in third ventricular cerebrospinal fluid of rabbits during fever and changes in body temperature

1980 • 128 citations

Anti-inflammatory steroids reduce tissue PG synthetase activity and enhance PG breakdown

1980 • 66 citations

A dissociation between fever and prostaglandin concentration in cerebrospinal fluid.

1975 • 63 citations

Prostaglandins of the E and F series in rabbit cerebrospinal fluid during fever induced by Newcastle disease virus,E. coli-endotoxin, or endogenous Pyrogen

1974 • 55 citations

The Ferrier Lecture, 1974 Body temperature and fever : changes in our views during the last decade

1975 • 48 citations

EFFECT OF p‐BROMOPHENACYL BROMIDE, AN INHIBITOR OF PHOSPHOLIPASE A₂, ON ARACHIDONIC ACID RELEASE AND PROSTAGLANDIN SYNTHESIS BY THE GUINEA‐PIG UTERUS in vitro

1977 • 48 citations

Effects of prostaglandin antagonism on sodium arachidonate fever in rabbits.

1977 • 47 citations

Hyperthermic effects of arachidonic acid, prostaglandins E2 and F2? in rats

1978 • 38 citations

Fever produced by intrahypothalamic pyrogen: Effect of protein synthesis inhibition by anisomycin

1979 • 33 citations

Antagonism by antipyretics of the hyperthermic effect of a prostaglandin precursor, sodium arachidonate, in the cat.

1976 • 31 citations

The site of action of corticosteroid antipyresis in the rabbit.

1980 • 30 citations

FACTORS AFFECTING PROSTACYCLIN FORMATION BY THE RAT PREGNANT MYOMETRIUM

1980 • 29 citations

Suppression of fever in rabbits by a protein synthesis inhibitor, anisomycin.

1980 • 28 citations

Influence of endogenous pyrogen on the cerebral prostaglandin-synthetase system

1976 • 24 citations

Mechanism of protection against arachidonate induced sudden death by glucocorticoid

1981 • 19 citations

Inhibition, by trichothecene antibiotics, of brain protein synthesis and fever in rabbits.

1982 • 19 citations

Analogs of endoperoxide precursors of prostaglandins: Failure to affect body temperature when injected into primary and secondary central temperature controls

1977 • 18 citations

Further observations on the suppression of fever in rabbits by intracerebral action of anisomycin.

1982 • 14 citations

Hyperthermic effect of prostacyclin injected into the third cerebral ventricle of the cat

1979 • 13 citations

Intraventricular microinjections of a stable analogue of prostaglandin endoperoxide cause fever in rabbits.

1979 • 10 citations