Molecular cloning of amyloid cDNA derived from mRNA of the Alzheimer disease brain: coding and noncoding regions of the fetal precursor mRNA are expressed in the cortex.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

Amyloid Deposits and Amyloidosis

1980 • 1,787 citations

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1984 • 1,633 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides.

1987 • 589 citations

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

1984 • 352 citations

Localization of Amyloid β Protein Messenger RNA in Brains from Patients with Alzheimer's Disease

1987 • 297 citations

Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects

1966 • 293 citations

Alzheimer's disease: a correlative study.

1986 • 269 citations

β Amyloid Gene Duplication in Alzheimer's Disease and Karyotypically Normal Down Syndrome

1987 • 187 citations

Alzheimer's Disease Brain: Alterations in RNA Levels and in a Ribonuclease-Inhibitor Complex

1984 • 173 citations

Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques

1983 • 173 citations

Alterations in protein synthetic capability of nerve cells in Alzheimer's disease.

1981 • 96 citations

THE QUANTITATIVE ASSESSMENT OF LIPOFUSCIN PIGMENT, CYTOPLASMIC RNA AND NUCLEOLAR VOLUME IN SENILE DEMENTIA

1978 • 88 citations

NEUROFIBRILLARY PATHOLOGY AND PROTEIN SYNTHETIC CAPABILITY IN NERVE CELLS IN ALZHEIMER'S DISEASE

1981 • 43 citations

In Vitro Synthesis of Human Brain Proteins Including Tubulin and Actin by Purified Postmortem Polysomes

1981 • 43 citations

In Vitro Synthesis of Polypeptides of Moderately Large Size by Poly(A)‐Containing Messenger RNA from Postmortem Human Brain and Mouse Brain

1983 • 34 citations

Quantitative studies of neuronal RNA on the subiculum of demented old individuals

1979 • 31 citations

Chapter 19 Transcriptional and translational regulatory mechanisms during normal aging of the mammalian brain and in Alzheimer's disease

1986 • 25 citations

Brain messenger RNA levels and ribonuclease activity in Alzheimer's disease

1987 • 17 citations