Fine specificity of CD4+ T cell responses to the dominant encephalitogenic PLP 139-151 peptide in SJL/J mice

Statistical Methods in Medical Research.

1972 • 4,731 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 • 670 citations

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

1993 • 595 citations

Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes.

1981 • 592 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

1989 • 372 citations

Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis

1984 • 340 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

The Developmental Biology of T Lymphocytes

1988 • 300 citations

Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein

1992 • 231 citations

Relapsing experimental allergic encephalomyelitis in the SJL/J mouse.

1981 • 197 citations

A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis.

1991 • 165 citations

Chronologic neuropathology of relapsing experimental allergic encephalomyelitis in the mouse.

1982 • 164 citations

Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides.

1990 • 140 citations

Induction of experimental allergic encephalomyelitis in PL/J and (SJL/J x PL/J)F1 mice by myelin basic protein and its peptides: localization of a second encephalitogenic determinant.

1983 • 137 citations

Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.

1989 • 135 citations

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas.

1992 • 131 citations

Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis.

1991 • 130 citations

Cytolytic T Lymphocytes

1983 • 119 citations

Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules.

1990 • 118 citations

Induction of experimental allergic encephalomyelitis in Lewis rats with purified synthetic peptides: delineation of antigenic determinants for encephalitogenicity, in vitro activation of cellular transfer, and proliferation of lymphocytes.

1985 • 88 citations

Delayed, relapsing experimental allergic encephalomyelitis in mice.

1981 • 87 citations

Myelin proteolipid protein induces demyelinating disease in mice

1987 • 83 citations

Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction.

1990 • 77 citations

Specific immune regulation of chronic-relapsing experimental allergic encephalomyelitis in mice.

1988 • 69 citations

Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. II. Fine specificity of effector T cell inhibition.

1992 • 66 citations

Immunological Disease

1970 • 62 citations

Successful treatment of paralytic relapses in adoptive experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance.

1991 • 53 citations

Failure to find holes in the T-cell repertoire

1987 • 51 citations

Preparation of Proteolipids

1978 • 43 citations

Antigen-Specific Tolerance as a Therapy for Experimental Autoimmune Encephalomyelitis

1992 • 43 citations

Dissociation between lymphocyte activation for proliferation and for the capacity to adoptively transfer uveoretinitis.

1987 • 40 citations

Encephalitogenic and proliferative responses of Lewis rat lymphocytes distinguished by position 75- and 80-substituted peptides of myelin basic protein.

1989 • 30 citations

Autoimmune Demyelination in the Central Nervous Systema

1988 • 27 citations

Monoclonal antibody-induced inhibition of relapsing EAE in SJL/J mice correlates with inhibition of neuroantigen-specific cell-mediated immune responses☆

1987 • 20 citations

Inhibition of Antigen PresentationIn VitroandIn Vivoby MHC Antagonist Peptides

1990 • 7 citations

Differential recognition of sequences within the encephalitogenic region of myelin basic protein capable of eliciting cell-mediated immune responses in experimental autoimmune encephalomyelitis

1993 • 4 citations