Monoclonal antibody-induced inhibition of relapsing EAE in SJL/J mice correlates with inhibition of neuroantigen-specific cell-mediated immune responses☆

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes.

1981 • 592 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice.

1977 • 361 citations

Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis

1984 • 340 citations

Reversal of Experimental Allergic Encephalomyelitis with Monoclonal Antibody to a T-Cell Subset Marker

1985 • 328 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Multiple sclerosis☆Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages

1983 • 309 citations

Induction of tolerance by monoclonal antibody therapy

1986 • 307 citations

Primary demyelination in Theiler's virus infection. An ultrastructural study.

1975 • 273 citations

Statistical Methods in Research

1950 • 227 citations

Experimental allergic encephalomyelitis: successful treatment in vivo with a monoclonal antibody that recognizes T helper cells.

1984 • 222 citations

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.

1985 • 207 citations

Relapsing experimental allergic encephalomyelitis in the SJL/J mouse.

1981 • 197 citations

Multiple Sclerosis as a Disease of Immune Regulation

1984 • 169 citations

Chronologic neuropathology of relapsing experimental allergic encephalomyelitis in the mouse.

1982 • 164 citations

Chronic Relapsing Experimental Allergic Encephalomyelitis

1979 • 147 citations

Experimental Autoimmune Encephalomyelitis in Mice: Immunologic Response to Mouse Spinal Cord and Myelin Basic Proteins

1975 • 145 citations

Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies

1980 • 136 citations

Relapsing murine experimental allergic encephalomyelitis induced by myelin basic protein.

1983 • 130 citations

Experimental Allergic Encephalomyelitis in Inbred and Outbred Mice

1973 • 121 citations

Long-term humoral unresponsiveness in vivo, induced by treatment with monoclonal antibody against L3T4.

1986 • 115 citations

Experimental allergic encephalomyelitis mediated by murine encephalitogenic T cell lines specific for myelin proteolipid apoprotein.

1987 • 115 citations

Chronic neurologic disease in Theiler's virus infection of SJL/J mice

1976 • 108 citations

CORRELATION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS WITH DELAYED‐TYPE SKIN SENSITIVITY TO SPECIFIC HOMOLOGOUS ENCEPHALITOGEN^*

1965 • 107 citations

Purification of Theiler's Murine Encephalomyelitis Virus and Analysis of the Structural Virion Polypeptides: Correlation of the Polypeptide Profile with Virulence

1980 • 101 citations

Encephalitogenic activity of guinea pig myelin basic protein in the SJL mouse.

1982 • 95 citations

The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation.

1985 • 89 citations

Studies on the Species-Variability of Experimental Allergic Encephalomyelitis in Guinea Pigs and Rats

1974 • 87 citations

Delayed, relapsing experimental allergic encephalomyelitis in mice.

1981 • 87 citations

Characterization of T cell lines and clones from SJL/J and (BALB/c x SJL/J)F1 mice specific for myelin basic protein.

1985 • 68 citations

DM-20, a proteolipid apoprotein, is an encephalitogen of acute and relapsing autoimmune encephalomyelitis in mice.

1986 • 67 citations

Treatment of established chronic relapsing experimental allergic encephalomyelitis with anti-L3T4 antibodies.

1986 • 67 citations

Experimental allergic encephalomyelitis — Migration of early T cells from the circulation into the central nervous system

1978 • 66 citations

In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity

1985 • 59 citations

Development of acute autoimmune encephalomyelitis in mice: Factors regulating the effector phase of the disease

1982 • 56 citations

T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis

1984 • 53 citations

Studies of experimental allergic encephalomyelitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice.

1986 • 53 citations

Genetic control of susceptibility to experimental allergic encephalomyelitis in mice

1979 • 51 citations

The pathogenesis and therapy of multiple sclerosis is based upon the requirement of a combination of myelin antigens for autoimmune demyelination

1982 • 48 citations

Preparation of Proteolipids

1978 • 43 citations

Relapsing experimental allergic encephalomyelitis an autoimmune model of multiple sclerosis

1985 • 40 citations

Experimental allergic encephalomyelitis in inbred guinea pigs: Correlation of decrease in early T cells with clinical signs in suppressed and unsuppressed animals

1977 • 39 citations

Experimental autoimmune encephalomyelitis mediated by T-cell line

1984 • 31 citations

Delayed Hypersensitivity to Myelin Basic Protein in the Passive Transfer of Experimental Allergic Encephalomyelitis

1968 • 31 citations

Passive transfer of experimental allergic encephalomyelitis by myelin basic protein-specific L3T4+ T cell clones possessing several functions.

1986 • 30 citations

The immunologic response in mice unresponsive to experimental allergic encephalomyelitis.

1981 • 19 citations

Therapy of rat autoimmune disease by a monoclonal antibody specific for T lymphoblasts.

1986 • 16 citations

Ia restriction of murine encephalitogenic T-cell lines in vitro and in vivo

1985 • 14 citations

Modulation of experimental allergic encephalomyelitis in lewis rats by monoclonal anti-T cell antibodies

1984 • 14 citations

T cell line-mediated EAE: prevention and therapy by a monoclonal antibody specific for T lymphoblasts

1987 • 9 citations

Genetic control of myelin basic protein-induced experimental allergic encephalomyelitis in mice.

1984 • 8 citations

Anti-T cell monoclonal antibodies in vivo. II. Modulation of acute and chronic experimental allergic encephalomyelitis (EAE) in guinea pigs.

1987 • 6 citations