Testosterone Diminishes the Proarrhythmic Effects of Dofetilide in Normal Female Rabbits

An analysis of the time-relations of electrocardiograms

1920 • 3,889 citations

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

1996 • 1,741 citations

Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones

1998 • 1,145 citations

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1993 • 843 citations

Female Gender as a Risk Factor for Torsades de Pointes Associated With Cardiovascular Drugs

1993 • 702 citations

Sex differences in the evolution of the electrocardiographic QT interval with age.

1992 • 634 citations

Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide.

1993 • 512 citations

Electrocardiographic quantitation of ventricular repolarization.

1989 • 403 citations

Sex Hormones Prolong the QT Interval and Downregulate Potassium Channel Expression in the Rabbit Heart

1996 • 368 citations

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide.

1992 • 316 citations

Drug-Induced QT Prolongation in Women During the Menstrual Cycle

2001 • 301 citations

A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression.

1993 • 265 citations

Sex differences on the electrocardiographic pattern of cardiac repolarization: Possible role of testosterone

2000 • 251 citations

Female Gender as a Risk Factor for Drug-Induced Cardiac Arrhythmias: Evaluation of Clinical and Experimental Evidence

1998 • 228 citations

Gender difference in the cycle length-dependent QT and potassium currents in rabbits.

1998 • 208 citations

Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain.

1994 • 202 citations

Sex, hormones, and repolarization

2002 • 189 citations

Impact of Sex and Gonadal Steroids on Prolongation of Ventricular Repolarization and Arrhythmias Induced by I _K -Blocking Drugs

2001 • 139 citations

IK of rabbit ventricle is composed of two currents: evidence for IKs

1996 • 131 citations

QT interval-heart rate relation during exercise in normal men and women: Definition by linear regression analysis

1996 • 124 citations

Effects of gonadal steroids on gender-related differences in transmural dispersion of L-type calcium current

2002 • 109 citations

JTc prolongation with d,l-sotalol in women versus men

1999 • 96 citations

Use-dependent block of the delayed K+ current in rabbit ventricular myocytes

1993 • 77 citations

Testosterone-mediated modulation of HERG blockade by proarrhythmic agents11Abbreviations: TdP, torsades de pointes; HERG, human ether-a-go-go related gene; DMSO, dimethyl sulfoxide.

2001 • 58 citations

The prolongation of the action potential in mammalian ventricular muscle at rest

1982 • 4 citations