Dimerization Properties of Human BAD

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

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1993 • 3,111 citations

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Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

1995 • 2,114 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

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1996 • 1,456 citations

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

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1992 • 1,078 citations

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1996 • 921 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 860 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Induction of apoptosis by the Bcl-2 homologue Bak

1995 • 738 citations

Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product

1995 • 604 citations

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

1994 • 590 citations

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

1995 • 514 citations

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

1995 • 501 citations

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.

1995 • 491 citations

Bax-independent inhibition of apoptosis by Bcl-XL

1996 • 484 citations

Proapoptotic Protein Bax Heterodimerizes with Bcl-2 and Homodimerizes with Bax via a Novel Domain (BH3) Distinct from BH1 and BH2

1996 • 462 citations

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins.

1995 • 431 citations

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL

1997 • 381 citations

A Common Binding Site Mediates Heterodimerization and Homodimerization of Bcl-2 Family Members

1997 • 128 citations

Functional Dissection of the Human Bcl2 Protein: Sequence Requirements for Inhibition of Apoptosis

1996 • 126 citations

Apoptosis: Breaking the ICE

1994 • 46 citations

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1995 • 25 citations