Prognostic implication of proliferative markers MIB-1 and PC10 in esophageal squamous cell carcinoma

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

1983 • 2,745 citations

Monoclonal antibodies against recombinant parts of the Ki‐67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave‐processed formalin‐fixed paraffin sections

1992 • 1,484 citations

Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms

1990 • 1,454 citations

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins.

1993 • 756 citations

Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden

1993 • 595 citations

New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.

1993 • 380 citations

The assessment of cellular proliferation by immunohistochemistry: A review of currently available methods and their applications

1992 • 307 citations

Detection of the Ki‐67 antigen in fixed and wax‐embedded sections with the monoclonal antibody MIB1

1993 • 299 citations

The assessment of proliferating cell nuclear antigen (PCNA) immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S + G2 + M phase fraction (flow cytometric analysis) and prognosis

1991 • 220 citations

Update on proliferation-associated antibodies applicable to formalin-fixed paraffin-embedded tissue and their clinical applications

1993 • 129 citations

Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy

1994 • 113 citations

A comparison of proliferating cell nuclear antigen (PCNA) immunostaining, nucleolar organizer region (AGNOR) staining, and histological grading in gastrointestinal stromal tumours

1992 • 108 citations

Prognostic significance of human papillomavirus genomes (type‐16, ‐18) and aberrant expression of p53 protein in human esophageal cancer

1993 • 104 citations

Update on proliferation-associated antibodies applicable to formalin-fixed paraffin-embedded tissue and their clinical applications

1993 • 102 citations

Changes in p⁵³ and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric‐cardia carcinogenesis

1994 • 96 citations

Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy

1994 • 94 citations

Proliferating cell nuclear antigen in oesophageal diseases; correlation with transforming growth factor alpha expression.

1992 • 70 citations

Assignment of the human Ki-67 gene (MKI67)to 10q25-qter

1991 • 68 citations

Expression of p53 in human esophageal carcinoma: An immunohistochemical study with correlation to proliferating cell nuclear antigen expression

1992 • 64 citations

Vascularization of carcinomas of the esophagus and its correlation with tumor proliferation.

1994 • 59 citations

Assessment of proliferative activity in carcinomas of the human alimentary tract by Ki‐67 immunostaining

1991 • 44 citations

p53 gene mutants expression, cellular proliferation and differentiation in oesophageal carcinoma and non-cancerous epithelium.

1994 • 20 citations

Definitions and Explanatory Notes

1990 • 17 citations

Immunohistochemical Determination of Growth Fraction in Human Tumors

1989 • 15 citations

Nucleolar organizer regions in human esophageal disorders: comparison with proliferating cell nuclear antigen by immunostaining.

1992 • 13 citations

The Proliferative Cell Fraction in Cytology Specimens: A Study of Human Esophageal Carcinoma

1992 • 10 citations

Production of a monoclonal antibody (IND.64) identifying a cell cycle‐associated antigen using spleen cells from nude mice bearing ichikawa tumour

1992 • 5 citations