Nucleotide sequence of the first cosmid from the Mycobacterium leprae genome project: structure and function of the Rif‐Str regions

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: A proposal for a synonymous codon choice that is optimal for the E. coli translational system

1981 • 1,405 citations

The catalase—peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

1992 • 1,287 citations

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

1990 • 1,231 citations

Prosite: a dictionary of sites and patterns in proteins

1992 • 952 citations

The complete DNA sequence of yeast chromosome III

1992 • 851 citations

A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria

1986 • 753 citations

Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance

1988 • 670 citations

Tuberculosis in developing countries: burden, intervention and cost.

1990 • 600 citations

The guanine and cytosine content of genomic DNA and bacterial evolution.

1987 • 587 citations

The C. elegans genome sequencing project: a beginning

1992 • 496 citations

Lysogeny and transformation in mycobacteria: stable expression of foreign genes.

1988 • 321 citations

Recent evidence for evolution of the genetic code

1992 • 319 citations

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV.

1990 • 199 citations

Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA.

1988 • 183 citations

Nucleic acid and protein sequence analysis: a practical approach

1988 • 180 citations

Molecular analysis of DNA and construction of genomic libraries of Mycobacterium leprae

1985 • 178 citations

Nucleotide sequence of the osmoregulatory proU operon of Escherichia coli

1989 • 146 citations

Sequence, organization, transcription and evolution of RNA polymerase subunit genes from the archaebacterial extreme halophiles Halobacterium halobium and Halococcus morrhuae

1989 • 137 citations

Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae

1993 • 112 citations

Organization and codon usage of the streptomycin operon in Micrococcus luteus, a bacterium with a high genomic G + C content

1987 • 95 citations

Yeast DNA 3′-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics.

1988 • 91 citations

Characterization of a bacteriocinogenic plasmid from Clostridium perfringens and molecular genetic analysis of the bacteriocin-encoding gene

1986 • 79 citations

Lorist6, a cosmid vector with BamHI, NotI, ScaI and Hind III cloning sites and altered neomycin phosphotransferase gene expression

1987 • 71 citations

Yeast DNA diesterase for 3′-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage.

1988 • 67 citations

Identification, sequencing, and expression of Mycobacterium leprae superoxide dismutase, a major antigen

1990 • 62 citations

Escherichia coli molecular genetic map (1500 kbp): update II

1991 • 62 citations

Nucleotide sequence of the nfo gene of Escherichia coli K-12

1988 • 45 citations

RECENT ADVANCES IN THE CHEMOTHERAPY OF LEPROSY

1990 • 43 citations

Sequence analysis of the peptide‐elongation factor EF‐2 gene, downstream from those of ribosomal proteins H‐S12 and H‐S7, from the archaebacterial extreme halophile, Halobacterium halobium

1989 • 37 citations

TheEuglena gracilischloroplastrpoBgene. Novel gene organization and transcription of the RNA polymerase subunit operon

1990 • 37 citations

Nucleotide sequence of the 16S rRNA fromMycobacterium leprae

1990 • 28 citations

Fusidic acid is highly active against extracellular and intracellular Mycobacterium leprae

1992 • 24 citations