Isolation and Characterization of Dek, a Drosophila Eph Receptor Protein Tyrosine Kinase

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

A Laboratory manual

1989 • 6,833 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways

1994 • 1,309 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Drosophila: a laboratory manual

1990 • 1,081 citations

Expression of baculovirus P35 prevents cell death in Drosophila

1994 • 1,037 citations

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate.

1994 • 1,032 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1993 • 984 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Insulin Resistance — Mechanisms, Syndromes, and Implications

1991 • 788 citations

Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance

1994 • 690 citations

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade

1997 • 625 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

1996 • 536 citations

From grasshopper to Drosophila: a common plan for neuronal development

1984 • 475 citations

Position effect variegation in Drosophila is associated with an altered chromatin structure.

1995 • 475 citations

An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system

1991 • 427 citations

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

1998 • 423 citations

Genes that control neuromuscular specificity in Drosophila

1993 • 413 citations

Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.

1991 • 385 citations

Drosophila: A laboratory manual

1990 • 350 citations

Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.

1996 • 334 citations

PDZs and Receptor/Channel Clustering: Rounding Up the Latest Suspects

1996 • 322 citations

The Taxonomy of Developmental Control in Caenorhabditis elegans

1998 • 304 citations

EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

1998 • 301 citations

SAM as a protein interaction domain involved in developmental regulation

1997 • 299 citations

A LIM-homeodomain combinatorial code for motor-neuron pathway selection

1999 • 294 citations

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1990 • 287 citations

The Drosophila islet Gene Governs Axon Pathfinding and Neurotransmitter Identity

1997 • 283 citations

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

1997 • 276 citations

The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans

1998 • 254 citations

The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS

1994 • 235 citations

apterous is a drosophila LIM domain gene required for the development of a subset of embryonic muscles

1992 • 227 citations

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

1998 • 202 citations

The Eph family in retinal axon guidance

1997 • 187 citations

Tau-beta-galactosidase, an axon-targeted fusion protein.

1994 • 162 citations

Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase

1998 • 151 citations

SAM: A novel motif in yeast sterile anddrosophilapolyhomeotic proteins

1995 • 148 citations

Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways

1994 • 147 citations

Signaling by Eph receptors and their ephrin ligands

1998 • 147 citations

Ligand Activation of ELK Receptor Tyrosine Kinase Promotes Its Association with Grb10 and Grb2 in Vascular Endothelial Cells

1996 • 145 citations

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

1998 • 126 citations

Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region

1998 • 123 citations

A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn.

1996 • 109 citations

Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors

1997 • 101 citations

The Eph family in the patterning of neural development

1997 • 95 citations

Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion.

1996 • 60 citations

The kinase-inactive PDGF beta-receptor mediates activation of the MAP kinase cascade via the endogenous PDGF alpha-receptor in HepG2 cells.

1996 • 8 citations