Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Serotonergic component of neuroleptic receptors

1978 • 621 citations

Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

1989 • 600 citations

Increased Serotonin2 and β-Adrenergic Receptor Binding in the Frontal Cortices of Suicide Victims

1986 • 552 citations

Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency

1980 • 543 citations

INCREASED DOPAMINE-RECEPTOR SENSITIVITY IN SCHIZOPHRENIA

1978 • 513 citations

Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT2 serotonergic receptors.

1981 • 511 citations

The Role of Serotonin in Schizophrenia

1988 • 368 citations

Serotonergic measures in the brains of suicide victims: 5-HT2 binding sites in the frontal cortex of suicide victims and control subjects

1989 • 316 citations

Dopamine receptors in human brain: Autoradiographic distribution of D2 sites

1989 • 298 citations

Neurotransmitter Receptors in Frontal Cortex of Schizophrenics

1979 • 249 citations

Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics

1986 • 225 citations

Brain 5-HT2 receptor binding sites in depressed suicide victims

1988 • 215 citations

Frontal lobe dysfunctions in schizophrenia—II. impairments of psychological and brain functions

1984 • 197 citations

Typical and atypical antipsychotic occupancy of D2 and S2 receptors: An autoradiographic analysis in rat brain

1986 • 177 citations

5‐Hydroxytryptamine receptor “families”

1989 • 160 citations

Biological Studies in Schizophrenia

1987 • 138 citations

Tritiated LSD Binding in Frontal Cortex in Schizophrenia

1981 • 125 citations

Autoradiographic localization of D1 and D2 dopamine receptors in the human brain

1988 • 124 citations

Effects of acute and chronic treatments with clozapine and haloperidol on serotonin (5-HT2) and dopamine (D2) receptors in the rat brain

1989 • 122 citations

Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain

1990 • 112 citations

Binding interactions of lysergic acid diethylamide and related agents with dopamine receptors in the brain.

1976 • 109 citations

Autoradiographic analysis of age-dependent changes in serotonin 5-HT2 receptors of the human brain postmortem

1990 • 92 citations

Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex

1989 • 91 citations

Differential Effect of Subchronic Treatment with Various Neuroleptic Agents on Serotonin₂ Receptors in Rat Cerebral Cortex

1986 • 80 citations

Loxapine and clozapine decrease serotonin (S2) but do not elevate dopamine (D2) receptor numbers in the rat brain

1984 • 74 citations

Autoradiographic localization and quantification of dopamine D2 receptors in normal human brain with [3H]N-n-propylnorapomorphine

1986 • 67 citations

Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action.

1983 • 67 citations

2-[125Iodo]LSD, a new ligand for the characterisation and localisation of 5-HT2 receptors

1984 • 65 citations

3H-spiperone binding in normal and schizophrenic post-mortem human brain

1978 • 63 citations

Characterization and localization of serotonin receptors in human brain postmortem

1986 • 61 citations

Neurotransmitter receptors in brain in schizophrenia

1981 • 61 citations

Regional and Cortical Laminar Distributions of Serotonin S₂, Benzodiazepine, Muscarinic, and Dopamine D₂ Receptors in Human Brain

1984 • 52 citations

Selective labeling of serotonin receptors by d-[3H]lysergic acid diethylamide in calf caudate.

1978 • 38 citations

Regional distribution of the dopamine D2 receptors in the mesotelencephalic dopamine neuron system of human brain

1985 • 35 citations

D-2 dopamine receptors in the frontal cortex of rat and human

1985 • 24 citations

Specific [3H]-spiroperidol binding sites in human prefrontal cortex: Potential site multiplicity and overall serotonin-like selectivity

1984 • 15 citations

Pharmacological characterization of binding sites identified in rat brain following in vivo administration of [³H]‐spiperone.

1987 • 12 citations

Evidence for the presence of D2 and 5-HT2 receptors in the human prefrontal cortex.

1982 • 12 citations