Structural Diversity of Domain Superfamilies in the CATH Database

Basic local alignment search tool

1990 • 87,358 citations

KEGG: Kyoto Encyclopedia of Genes and Genomes

1999 • 30,001 citations

KEGG: Kyoto Encyclopedia of Genes and Genomes

2000 • 26,574 citations

Computational Geometry: Algorithms and Applications

1997 • 4,614 citations

The Gene Ontology (GO) database and informatics resource

2003 • 4,254 citations

The COG database: an updated version includes eukaryotes

2003 • 4,151 citations

The Universal Protein Resource (UniProt)

2004 • 3,591 citations

CATH – a hierarchic classification of protein domain structures

1997 • 2,558 citations

The relation between the divergence of sequence and structure in proteins.

1986 • 2,373 citations

The α/β hydrolase fold

1992 • 2,024 citations

The lipocalin protein family: structure and function

1996 • 1,658 citations

Computational geometry: Algorithms and applications

1998 • 1,566 citations

The ENZYME database in 2000

2000 • 1,056 citations

How different amino acid sequences determine similar protein structures: The structure and evolutionary dynamics of the globins

1980 • 697 citations

Protein structure alignment

1989 • 683 citations

Evolution of function in protein superfamilies, from a structural perspective 1 1Edited by A. R. Fersht

2001 • 665 citations

Fold Change in Evolution of Protein Structures

2001 • 438 citations

PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE

2005 • 314 citations

Evolution of proteins formed by β-sheets

1982 • 275 citations

The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis

2004 • 257 citations

Analysis of insertions/deletions in protein structures

1992 • 241 citations

The κ-carrageenase of P. carrageenovora Features a Tunnel-Shaped Active Site

2001 • 192 citations

Structural Basis for the Recognition of Carbohydrates by Human Galectin-7^,

1998 • 191 citations

Comparison of conformational characteristics in structurally similar protein pairs

1993 • 171 citations

Lipocalins in drug discovery: From natural ligand-binding proteins to ‘anticalinsʼ

2005 • 169 citations

Structural Features can be Unconserved in Proteins with Similar Folds

1994 • 164 citations

Evolution of protein complexity: The blue copper-containing oxidases and related proteins

1993 • 159 citations

Quantifying the Similarities within Fold Space

2002 • 139 citations

Structural comparison of cupredoxin domains: Domain recycling to construct proteins with novel functions

1997 • 136 citations

Evolution of protein sequences and structures

1999 • 132 citations

The three–dimensional structure of glucose 6–phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 Å resolution

1994 • 127 citations

Automatic inference of protein quaternary structure from crystals

2003 • 97 citations

Recognizing the fold of a protein structure

2003 • 83 citations

CORA—Topological fingerprints for protein structural families

1999 • 63 citations

The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues

2000 • 62 citations

Functional information in SWISS-PROT: The basis for large-scale characterisation of protein sequences

2001 • 55 citations

Three-Dimensional Structure of Escherichia coli Dihydrodipicolinate Reductase

1995 • 55 citations

Assessing strategies for improved superfamily recognition

2005 • 23 citations

Analysis of conservation and substitutions of secondary structure elements within protein superfamilies

2000 • 22 citations