Antigen receptor‐induced apoptosis of human germinal center B cells is targeted to a centrocytic subset

A Theory of Self-Nonself Discrimination

1970 • 1,700 citations

Germinal Centers

1994 • 1,680 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

Analysis of somatic mutation in five B cell subsets of human tonsil.

1994 • 667 citations

A Role in B Cell Activation for CD22 and the Protein Tyrosine Phosphatase SHP

1995 • 551 citations

Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis

1991 • 525 citations

The CD19/CR2/TAPA-1 Complex of B Lymphocytes: Linking Natural to Acquired Immunity

1995 • 469 citations

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

1995 • 448 citations

Antigen-induced B-cell death and elimination during germinal-centre immune responses

1995 • 377 citations

Essential flexibility in the T-cell recognition of antigen

1996 • 330 citations

Self-Tolerance Checkpoints in B Lymphocyte Development

1995 • 329 citations

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells

1995 • 301 citations

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance.

1995 • 224 citations

Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40.

1994 • 210 citations

Identification of a subset of normal B cells with a Burkitt's lymphoma (BL)-like phenotype.

1987 • 209 citations

Cytokine expression by germinal center cells.

1993 • 161 citations

Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules.

1976 • 123 citations

Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

1996 • 117 citations

Isolated follicular dendritic cells: cytochemical antigen localization, Nomarski, SEM, and TEM morphology.

1985 • 111 citations

T cells within germinal centers are specific for the immunizing antigen.

1993 • 110 citations

Tolerance susceptibility of newly generating memory B cells.

1991 • 88 citations

Isolation and characteristics of tonsil centroblasts with reference to Ig class switching

1995 • 73 citations

Negative selection of human germinal center B cells by prolonged BCR cross-linking.

1996 • 68 citations

Phenotypic and functional heterogeneity of the IgD⁻ B cell compartment: identification of two major tonsillar B cell subsets

1993 • 65 citations

Co‐ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI‐231 cells from anti‐surface IgM‐induced apoptosis

1995 • 56 citations

Regulation of B-cell activation by CD45: a question of mechanism

1994 • 52 citations

Changes in CD44 Expression during B Cell Differentiation in the Human Tonsil

1995 • 49 citations

Polyclonal activation of immature B cells by preactivated T cells: the role of IL-4 and CD40 ligand

1993 • 35 citations

T lymphocytes that express CD4 and the alpha beta-T cell receptor but lack Thy-1. Preferential localization in Peyer's patches.

1990 • 30 citations

Durable elimination of high affinity, T cell-dependent antibodies by low molecular weight antigen arrays in vivo.

1995 • 16 citations

Suppression of the antibody response to a polymorphic peptide from the platelet alloantigen integrin beta3 with low molecular weight antigen arrays.

1996 • 6 citations