Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor

Epidermal growth factor.

1990 • 1,645 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

Autophosphorylation sites on the epidermal growth factor receptor

1984 • 730 citations

X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates.

1994 • 247 citations

Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor.

1985 • 232 citations

All Autophosphorylation Sites of Epidermal Growth Factor (EGF) Receptor and HER2/neu Are Located in Their Carboxyl-terminal Tails

1989 • 213 citations

Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates.

1990 • 193 citations

Evaluation of activity of putative superoxide dismutase mimics. Direct analysis by stopped-flow kinetics.

1993 • 101 citations

Irreversible oxidative inactivation of protein kinase C by photosensitive inhibitor calphostin C

1992 • 94 citations

Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor.

1990 • 92 citations

Oxidants induce phosphorylation of ribosomal protein S6.

1988 • 91 citations

Different responses to EGF in two human carcinoma cell lines, A431 and UCVA-1, possessing high numbers of EGF receptors

1984 • 55 citations

Identification of a human epidermal growth factor receptor-associated protein kinase as a new member of the mitogen-activated protein kinase/extracellular signal-regulated protein kinase family.

1993 • 46 citations

Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site.

1992 • 45 citations

Glycosylation of the Epidermal Growth Factor Receptor and Its Relationship to Membrane Transport and Ligand Binding1

1988 • 42 citations

Monoclonal antibody that immunoreacts with a subclass of human receptors for epidermal growth factor.

1985 • 41 citations

EGF: new tricks for an old growth factor

1993 • 33 citations

Serine 1002 is a site of in vivo and in vitro phosphorylation of the epidermal growth factor receptor.

1993 • 30 citations

Calphostin‐C stimulates epidermal growth factor receptor phosphorylation and internalization via light‐dependent mechanism

1994 • 23 citations

Subcellular localization of the EGF receptor maturation process

1989 • 11 citations

Lung cancer differentiation; implications for diagnosis and treatment

1993 • 8 citations

Light-Dependent Induction of Early-Response Gene Expression by Calphostin-C.

1994 • 6 citations

Lung cancer differentiation. Implications for diagnosis and treatment

1994 • 3 citations

Deleted Work

1955 • 0 citations