Enhanced T cell proliferation and increased responder frequency following delivery of antigen to the antigen-presenting cell; B cell dependency and use in detection of autoreactive T cells

C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity

1996 • 1,172 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

Signals and signs for lymphocyte responses

1994 • 868 citations

Receptor-Mediated Antigen Uptake and its Effect on Antigen Presentation to Class II-Restricted T Lymphocytes

1990 • 605 citations

B Cells Turn Off Virgin But Not Memory T Cells

1992 • 578 citations

Cytoplasmic Domain Heterogeneity and Functions of IgG Fc Receptors in B Lymphocytes

1992 • 462 citations

Limiting Dilution Analysis of Cells in the Immune System

1979 • 384 citations

B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo.

1995 • 303 citations

Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes

1992 • 275 citations

Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants.

1995 • 271 citations

Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

1995 • 257 citations

The B cell is the initiating antigen-presenting cell in peripheral lymph nodes.

1987 • 240 citations

Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.

1995 • 239 citations

Human tumor antigens recognized by T cells

1996 • 217 citations

B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes.

1993 • 210 citations

Limiting dilution analysis of human T cells: a useful clinical tool

1990 • 166 citations

T-Cell Responses to Autoantigens in IDDM: The Search for the Holy Grail

1996 • 164 citations

Major histocompatibility complex-restricted, polyclonal B cell responses resulting from helper T cell recognition of antiimmunoglobulin presented by small B lymphocytes.

1985 • 154 citations

Myelin basic protein–specific T lymphocytes in multiple sclerosis and controls: Precursor frequency, fine specificity, and cytotoxicity

1992 • 149 citations

Cell-mediated immune response to β casein in recent-onset insulin-dependent diabetes: implications for disease pathogenesis

1996 • 134 citations

Recombinant allergens for diagnosis and therapy of allergic diseases

1995 • 131 citations

Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosis

1986 • 124 citations

Cellular Immune Response to Diverse Islet Cell Antigens in IDDM

1996 • 123 citations

Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes.

1993 • 113 citations

T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.

1986 • 88 citations

Limiting dilution assay for human B cells based on their activation by mutant EL4 thymoma cells: total and anti‐malaria responder B cell frequencies

1987 • 76 citations

Cross-linking of Fc gamma receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel

1994 • 72 citations

Antigen presentation is enhanced by targeting antigen to the Fc epsilon RII by antigen-anti-Fc epsilon RII conjugates.

1994 • 55 citations

Cellular immune response to diverse islet cell antigens in IDDM

1996 • 48 citations

T-cell responses to autoantigens in IDDM. The search for the Holy Grail

1996 • 48 citations

Thyroid autoantigens and human T cell responses

1990 • 42 citations

Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fcε receptor by a recombinant human autoantibody Fab converted to IgE

1996 • 34 citations

FcγRII on Human B Cells Can Mediate Enhanced Antigen Presentation

1996 • 27 citations

T Cell Clones Generated from Patients with Type 1 Diabetes Using Interleukin-2 Proliferate to Human Islet Antigens

1994 • 17 citations

Peripheral B Lymphocyte Repertoire to Mitochondrial Antigen in Primary Biliary Cirrhosis - Positive Correlation Between the Disease Activity and the Frequency of Circulating B Lymphocytes Specific for Pyruvate Dehydroge Nase Complex

1995 • 13 citations

Enhanced proliferation of CD4+ T cells induced by dendritic cells following antigen uptake in the presence of specific antibody

1996 • 13 citations

HIV The immune response

1996 • 12 citations

Proliferative responses to insulin antigens in diabetics and controls.

1983 • 11 citations

Quantitative Analysis of Precursors Frequency of Rheumatoid Factor (RF) Producing Human B Cells

1988 • 9 citations

Role of T Lymphocytes in the Aetiology of Insulin-Dependent Diabetes

2015 • 2 citations