Betaine homocysteine methyltransferase: gene cloning and expression analysis in rat liver cirrhosis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Current protocols in molecular biology

1988 • 7,584 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat.

1984 • 669 citations

Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels

1979 • 564 citations

S –Adenosyl–L–Methionine Attenuates Alcohol–Induced Liver Injury in the Baboon

1990 • 336 citations

Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells.

1992 • 329 citations

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

2000 • 325 citations

Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity

1989 • 321 citations

Metabolism of Homocysteine Thiolactone in Human Cell Cultures

1997 • 296 citations

Purification, Kinetic Properties, and cDNA Cloning of Mammalian Betaine-Homocysteine Methyltransferase

1996 • 236 citations

Feeding S -adenosyl-l-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

1995 • 205 citations

Betaine–Homocysteine Methyltransferase Expression in Porcine and Human Tissues and Chromosomal Localization of the Human Gene

1997 • 203 citations

Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes.

1994 • 201 citations

Human Betaine–Homocysteine Methyltransferase Is a Zinc Metalloenzyme

1998 • 168 citations

S –Adenosylmethionine Treatment Prevents Carbon Tetrachloride—Induced S –Adenosylmethionine Synthetase Inactivation and Attenuates Liver Injury

1992 • 160 citations

The evolution of changes in quantitative liver function tests in a rat model of biliary cirrhosis: Correlation with morphometric measurement of hepatocyte mass

1987 • 146 citations

Betaine, ethanol, and the liver: A review

1996 • 124 citations

Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study.

1992 • 114 citations

Plasma homocyst(e)ine and arterial occlusive diseases: a mini-review

1995 • 112 citations

The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastage

1993 • 106 citations

Hyperhomocysteinemia in Liver Cirrhosis

2001 • 104 citations

Carbon tetrachloride–induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: Effect ofS-adenosylmethionine treatment

1995 • 89 citations

S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models

1992 • 81 citations

Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

1999 • 76 citations

Biochemistry and Pharmacology of S-Adenosyl-L-Methionine and Rationale for its Use in Liver Disease

1990 • 68 citations

Betaine-Homocysteine Methyltransferase-2: cDNA Cloning, Gene Sequence, Physical Mapping, and Expression of the Human and Mouse Genes

2000 • 55 citations

Experimental models of hepatic fibrosis in the rat.

1999 • 50 citations

Increased plasma homocysteine in liver cirrhosis

2001 • 50 citations

Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase

1999 • 26 citations

Cholestasis-induced alterations of the trans- and paracellular pathways in rat hepatocytes

1995 • 18 citations

The role of molecular biology in understanding ovarian cancer initiation and progression

2001 • 16 citations

THE FORMATION OF BETAINE FROM HYDROXYAMINO ACIDS ON METHYLATION

1941 • 12 citations

Application of mRNA Differential Display to Liver Cirrhosis: Reduced Fetuin Expression in Biliary Cirrhosis in the Rat

1996 • 8 citations

Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase

1999 • 7 citations