The Italian SEPSIS study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

1992 • 4,689 citations

Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

1991 • 1,611 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

The Pathogenesis of Sepsis

1991 • 1,376 citations

Multiple-Organ Failure

1985 • 1,314 citations

A simplified acute physiology score for ICU patients

1984 • 1,244 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.

1992 • 942 citations

A Controlled Clinical Trial of E5 Murine Monoclonal IgM Antibody to Endotoxin in the Treatment of Gram-Negative Sepsis

1991 • 741 citations

Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebocontrolled multicenter trial

1994 • 488 citations

Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis

1993 • 427 citations

Administration of Anti-TNF Antibody Improves Left Ventricular Function in Septic Shock Patients

1992 • 214 citations

Human neutrophil bactericidal/permeability-increasing protein reduces mortality rate from endotoxin challenge

1994 • 122 citations

Task Force: Guidelines for the problem of sepsis (ESICM)

1994 • 31 citations

The problem of sepsis

1994 • 25 citations

The problem of sepsis. An expert report of the European Society of Intensive Care Medicine.

1994 • 12 citations

HUMAN RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-1ra) INCREASES SURVIVAL TIME IN PATIENTS WITH SEPSIS SYNDROME AND END ORGAN DYSFUNCTION (EOD)

1994 • 5 citations