DNA-directed alkylating ligands as potential antitumor agents: sequence specificity of alkylation by intercalating aniline mustards

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Helix Geometry, Hydration, and G ⋅ A Mismatch in a B-DNA Decamer

1987 • 390 citations

DNA sequence selectivity of guanine–N7 alkylation by nitrogen mustards

1986 • 233 citations

Mechanisms of DNA sequence selective alkylation of guanine-N7 positions by nitrogen mustards

1987 • 178 citations

Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

1981 • 173 citations

Structural and Sequence-Dependent Aspects of Drug Intercalation Into Nucleic Acid

1984 • 167 citations

Dechlorination of l-phenylalanine mustard by sensitive and resistant tumor cells and its relationship to intracellular glutathione content

1983 • 154 citations

Molecular basis for sequence-specific DNA alkylation by CC-1065

1988 • 143 citations

Relationships between functionality and genetic toxicology of selected DNA-damaging agents

1984 • 123 citations

Relative reactivities for monofunctional nitrogen mustard alkylation of nucleic acid components

1968 • 78 citations

DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard

1990 • 78 citations

Interactions of DNA with divalent metal ions. I. ³¹P‐nmr studies

1982 • 70 citations

43. Aryl-2-halogenoalkylamines. Part I

1949 • 67 citations

Thermodynamic and kinetic parameters of ion condensation to polynucleotides

1976 • 63 citations

²⁵ Mg NMR in DNA solutions: Dominance of site binding effects

1980 • 59 citations

Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives

1989 • 45 citations

The mode of Mg⁺⁺binding to oligonucleotides. Inner sphere complexes as markers for recognition?

1979 • 44 citations

Use of an indicator sequence of human DNA to study DNA damage by methylbis(2-chloroethyl)amine.

1980 • 40 citations

Mechanisms of reaction of benzo(a)pyrene-7,8-diol-9,10-epoxide with DNA in aqueous solutions

1984 • 39 citations

Étude ultrastructurale de particules ribonucléoprotéiques nucléaires isolées à partir du foie de rat

1968 • 38 citations

Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells

1988 • 37 citations

Therapeutic trial of aniline mustard in patients with advanced cancer. Comparison of therapeutic response with cytochemical assessment of tumor cell β‐glucuronidase activity

1976 • 32 citations

The molecular electrostatic potential of the B-DNA helix

1979 • 24 citations

Ion-induced DNA structure change in nucleosomes

1986 • 8 citations