Regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying human tyrosine hydroxylase gene

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Tyrosine Hydroxylase

1964 • 2,038 citations

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART.

1965 • 1,002 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography

1979 • 235 citations

In vivo enhancement of tyrosine hydroxylation in rat striatum by tetrahydrobiopterin

1974 • 180 citations

Phosphorylation and activation of tyrosine hydroxylase mediate the cAMP-induced increase in catecholamine biosynthesis in adrenal chromaffin cells.

1982 • 177 citations

6R-l-Erythro-5,6,7,8-tetrahydrobiopterin as a regulator of dopamine and serotonin biosynthesis in the rat brain

1985 • 122 citations

Tissue-specific and high-level expression of the human tyrosine hydroxylase gene in transgenic mice

1991 • 115 citations

In vitro phosphorylation of bovine adrenal tyrosine hydroxylase by adenosine 3‘:5‘-monophosphate-dependent protein kinase.

1979 • 104 citations

Identification of protein phosphatase 2A as the major tyrosine hydroxylase phosphatase in adrenal medulla and corpus striatum: evidence from the effects of okadaic acid

1989 • 103 citations

Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in parkinsonian brain

1988 • 88 citations

Tyrosine Hydroxylase from Bovine Striatum: Catalytic Properties of the Phosphorylated and Nonphosphorylated Forms of the Purified Enzyme

1982 • 57 citations

Effect of Cyclic AMP‐Dependent Protein Phosphorylating Conditions on the pH‐Dependent Activity of Tyrosine Hydroxylase from Beef and Rat Striata

1981 • 57 citations

Studies on Tyrosine Hydroxylase System in Rat Brain Slices Using High-Performance Liquid Chromatography with Electrochemical Detection

1983 • 51 citations

An integrated scheme for the simultaneous determination of biogenic amines, precursor amino acids, and related metabolites by liquid chromatography with electrochemical detection

1984 • 36 citations

An integrated scheme for the simultaneous determination of biogenic amines, precursor amino acids, and related metabolites by liquid chromatography with electrochemical detection

1998 • 34 citations

Mechanism of tyrosine hydroxylase activation by phosphorylation

1982 • 25 citations