Tyrosine Hydroxylase from Bovine Striatum: Catalytic Properties of the Phosphorylated and Nonphosphorylated Forms of the Purified Enzyme

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Tyrosine Hydroxylase

1964 • 2,038 citations

Enzyme Kinetics Behavior and analysis of rapid equilibrium and steady state enzyme systems

1975 • 1,447 citations

Data for Biochemical Research.

1969 • 1,308 citations

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART.

1965 • 1,002 citations

Assay of tyrosine hydroxylase by coupled decarboxylation of dopa formed from 1-14C-l-tyrosine

1971 • 461 citations

Rapid protein kinase assay using phosphocellulose-paper absorption

1975 • 363 citations

Studies on the Mechanism of the Enzymatic Conversion of Phenylalanine to Tyrosine

1959 • 356 citations

Inhibitors of purified beef adrenal tyrosine hydroxylase

1965 • 327 citations

Purification and characterization of the catalytic subunit of adenosine 3':5'-cyclic monophosphate-dependent protein kinase from bovine liver

1976 • 295 citations

Purification and characterization of tyrosine hydroxylase from a clonal pheochromocytoma cell line.

1980 • 292 citations

Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation.

1978 • 286 citations

Selective release of newly synthesized norepinephrine from the cat spleen during sympathetic nerve stimulation.

1968 • 242 citations

Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase.

1980 • 189 citations

ATP, cyclic AMP, and magnesium increase the affinity of rat striatal tyrosine hydroxylase for its cofactor.

1975 • 184 citations

Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.

1975 • 179 citations

A Kinetic Study of Bovine Adrenal Tyrosine Hydroxylase

1966 • 167 citations

Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.

1978 • 167 citations

Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP

1974 • 161 citations

PTERIN-REQUIRING AROMATIC AMINO ACID HYDROXYLASES

1974 • 134 citations

The stimulation of partially purified bovine caudate tyrosine hydroxylase by phosphatidyl-L-serine

1974 • 118 citations

In vitro translation of mRNA from rat pheochromocytoma tumors, characterization of tyrosine hydroxylase

1981 • 102 citations

Evidence for the lack of direct phosphorylation of bovine caudate tyrosine hydroxylase following activation by exposure to enzymatic phosphorylating conditions

1975 • 93 citations

Evaluation of the biochemical effects produced in vivo by inhibitors of the three enzymes involved in norepinephrine biosynthesis.

1966 • 89 citations

The regional distribution of hydroxylase cofactor in rat brain

1979 • 83 citations

Regulation of bovine adrenal tyrosine 3-monooxygenase by phosphorylation-dephosphorylation reaction, catalyzed by adenosine 3‘:5‘-monophosphate-dependent protein kinase and phosphoprotein phosphatase.

1979 • 83 citations

Rat Brain Tyrosine Hydroxylase

1973 • 69 citations

Activation of tyrosine hydroxylase by polyanions and salts An electrostatic effect

1976 • 68 citations

Redundant Mechanisms Regulating Brain Tyrosine and Tryptophan Hydroxylases

1978 • 65 citations

Synthesis of Adrenal Catecholamines in Rats During and After Immobilization Stress

1971 • 65 citations

A simple radioisotope assay for phenylalanine hydroxylase cofactor

1967 • 64 citations

Isolation and characterization of a tyrosine hydroxylase cofactor from bovine adrenal medulla.

1971 • 62 citations

Soluble, Membrane-bound, and Detergent-solubilized Rat Striatal Tyrosine Hydroxylase

1973 • 62 citations

Tyrosine hydroxylase: studies on the phosphorylation of a purified preparation of the brain enzyme by the cyclic AMP-dependent protein kinase.

1981 • 61 citations

Studies on phenylalanine and tyrosine hydroxylation by rat brain tyrosine hydroxylase

1976 • 61 citations

Phospholipid-induced activation of tyrosine hydroxylase from rat brain striatal synaptosomes

1976 • 54 citations

Catecholamine storage particles in the central nervous system.

1966 • 45 citations

2-Amino-4-hydroxy-6-methyl-7,8-dihydropteridine as a Model for Dihydrofolate^*

1967 • 37 citations

Thermal Denaturation of Native Striatal Tyrosine Hydroxylase: Increased Thermolability of the Phosphorylated Form of the Enzyme

1981 • 35 citations

Feedback Inhibition of Tyrosine Hydroxylase from Five Regions of Rat Brain by 2‐Hydroxyestradiol and Dihy droxy pheny lalanine

1980 • 27 citations

Interaction of tyrosine hydroxylase with tubulin

1980 • 16 citations

Studies on a Molecular Basis for the Heparin‐Induced Regulation of Enzymatic Activity of Mouse Striatal Tyrosine Hydroxylase In Vitro. Inhibition of Heparin Activation and of the Enzyme by Poly‐L‐lysyltyrosine and Poly‐L‐lysylphenylalanine and Their Constituent Peptides

1980 • 14 citations

Release of Monoamines in the Central Nervous System

1970 • 13 citations

In vitro phosphorylation of a purified preparation of bovine corpus striatal tyrosine hydroxylase.

1978 • 12 citations

PROPERTIES OF TYROSINE HYDROXYLASE IN PERIPHERAL NERVES

1975 • 11 citations

TYROSINE HYDROXYLASE FROM BRAIN: PHOSPHORYLATION OF THE ENZYME BY CYCLIC AMP-DEPENDENT PROTEIN KINASE

1979 • 10 citations

SIMILARITIES BETWEEN THE IN VIVO ACTIVATION OF ADRENAL TYROSINE HYDROXYLASE AND THE IN VITRO ACTIVATION OF THE ENZYME BY AN ADENOSINE 3′,5′-MONOPHOSPHATE DEPENDENT PROTEIN PHOSPHORYLATING SYSTEM

1979 • 6 citations

Release of Monoamines in the Central Nervous System

1970 • 3 citations