A fly's eye view of biology

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The development of Drosophila melanogaster

1994 • 3,057 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila

1995 • 1,563 citations

Expression of baculovirus P35 prevents cell death in Drosophila

1994 • 1,037 citations

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes.

1996 • 564 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

The Drosophila Gene hid Is a Direct Molecular Target of Ras-Dependent Survival Signaling

1998 • 477 citations

Systematic gain-of-function genetics in Drosophila

1998 • 467 citations

The Rho GTPase and a Putative RhoGEF Mediate a Signaling Pathway for the Cell Shape Changes in Drosophila Gastrulation

1997 • 384 citations

Ras Promotes Cell Survival in Drosophila by Downregulating hid Expression

1998 • 378 citations

Cell death in normal and rough eye mutants of Drosophila

1991 • 364 citations

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

1994 • 346 citations

KSR, a novel protein kinase required for RAS signal transduction

1995 • 335 citations

Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway

1995 • 327 citations

Signalling by the sevenless protein tyrosine kinase is mimicked by Rasl activation

1992 • 315 citations

A Cyclin-Dependent Kinase Inhibitor, Dacapo, Is Necessary for Timely Exit from the Cell Cycle during Drosophila Embryogenesis

1996 • 314 citations

strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila

1998 • 310 citations

Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues

1998 • 295 citations

Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.

1991 • 248 citations

A Screen for Genes That Function Downstream of Ras1 During Drosophila Eye Development

1996 • 246 citations

Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster.

1990 • 227 citations

CNK, a RAF-Binding Multidomain Protein Required for RAS Signaling

1998 • 162 citations

Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery

1998 • 159 citations

Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants

1998 • 157 citations

Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye.

1996 • 118 citations

4 Eye Development in Drosophila: Formation of the Eye Field and Control of Differentiation

1998 • 106 citations

eyelidantagonizes wingless signaling during Drosophiladevelopment and has homology to the Bright family of DNA-binding proteins

1997 • 104 citations

Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A.

1997 • 104 citations

P element insertion-dependent gene activation in the Drosophila eye

1997 • 102 citations

A Genetic Screen to Identify Components of the sina Signaling Pathway in Drosophila Eye Development

1998 • 100 citations

The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements.

1989 • 99 citations

In situ inhibition of vesicle transport and protein processing in the dominant negative Rab1 mutant of Drosophila

1997 • 96 citations

Facing death in the fly: genetic analysis of apoptosis in Drosophila

1997 • 82 citations

roughex down-regulates G2 cyclins in G1.

1997 • 73 citations

Rab6 Regulation of Rhodopsin Transport inDrosophila

1998 • 70 citations

Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster.

1992 • 67 citations

marbles mutants: uncoupling cell determination and nuclear migration in the developing Drosophila eye

1994 • 65 citations

Domain requirements for the Dock adapter protein in growth- cone signaling

1998 • 54 citations

Confrontation of scabrous expressing and non-expressing cells is essential for normal ommatidial spacing in the Drosophila eye

1994 • 46 citations

Small GTPases Minireview Series

1998 • 44 citations

A modifier screen in the eye reveals control genes for Krüppel activity in the Drosophila embryo

1998 • 35 citations

Analysis of the enhancer element that controls expression of sevenless in the developing Drosophila eye.

1991 • 34 citations

The genetics of visual system development in Drosophila: specification, connectivity and asymmetry

1997 • 28 citations

The Drosophila genome project: a progress report

1998 • 27 citations

Ras1-Mediated Photoreceptor Development in Drosophila

1997 • 17 citations