Radiation-induced Potentially Lethal Damage: DNA Lesions Susceptible to Fixation

International Journal of Radiation Biology

1959 • 1,730 citations

Radiation Biology in Cancer Research

1980 • 782 citations

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1979 • 577 citations

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control

1976 • 518 citations

The repair of double-strand breaks in DNA: A model involving recombination

1976 • 499 citations

Hyperthermia and Cancer

1982 • 474 citations

Lethal and Potentially Lethal Lesions Induced by Radiation --- A Unified Repair Model

1986 • 469 citations

Changes in X-ray Sensitivity of HeLa Cells during the Division Cycle

1961 • 440 citations

Repair of Potentially Lethal Damage in X-Irradiated HeLa Cells¹

2012 • 407 citations

X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining

1984 • 379 citations

X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents

1983 • 345 citations

The Level of Induced DNA Double-strand Breakage Correlates with Cell Killing after X-irradiation

1985 • 316 citations

Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations

1984 • 313 citations

Repair of Potentially Lethal Damage in X-Irradiated HeLa Cells

1966 • 310 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

On the Nature of a Defect in Cells from Individuals with Ataxia-Telangiectasia

1985 • 298 citations

Molecular mechanisms involved in the production of cromosomal aberrations II. Utilization of neurospora endonuclease for the study of aberration production by X-rays in G1 and G2 stages of the cell cycle

1980 • 280 citations

Evidence for DNA Double-Strand Breaks as the Critical Lesions in Yeast Cells Irradiated with Sparsely or Densely Ionizing Radiation under Oxic or Anoxic Conditions

1981 • 271 citations

Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells

1985 • 271 citations

The Relationship between Chromosome Aberrations and Low LET Radiation Dose to Human Lymphocytes

1975 • 226 citations

Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.

1972 • 226 citations

DNA Double Strand Breaks in Ehrlich Ascites Tumour Cells at Low Doses of X-rays. II. Can Cell Death be Attributed to Double Strand Breaks?

1982 • 200 citations

Induction of DNA double-strand breaks by X-rays in a radiosensitive strain of the yeast Saccharomyces cerevisiae

1975 • 199 citations

X-Ray—Induced Breakage and Rejoining of Human Interphase Chromosomes

1983 • 197 citations

Repair of Potentially Lethal Radiation DamageIn VitroandIn Vivo

1973 • 194 citations

Comparison of Lethality and Chromosomal Damage Induced by X-Rays in Synchronized Chinese Hamster Cells In Vitro

1970 • 189 citations

Ataxia Telangiectasia: Genetics, Neuropathology, and Immunology of a Degenerative Disease of Childhood

1987 • 187 citations

Chromosomal Aberrations and Mortality of X-Irradiated Mammalian Cells: Emphasis on Repair

1971 • 183 citations

The radiosensitivity of melanoma cells in culture

1971 • 176 citations

Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.

1986 • 176 citations

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

1983 • 170 citations

The Action of Caffeine on X-Irradiated HeLa Cells: III. Enhancement of X-Ray-Induced Killing during G 2 Arrest

1978 • 160 citations

Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum

1978 • 159 citations

Chromosome aberrations and radiation-induced cell death

1973 • 156 citations

Advances in radiation biology

1975 • 149 citations

Enzymatic Restriction of Mammalian Cell DNA: Evidence for Double-strand Breaks as Potentially Lethal Lesions

1985 • 146 citations

X-ray-induced Chromosome Damage in Live Mammalian Cells, and Improved Measurements of Its Effects on Their Colony-forming Ability

1982 • 135 citations

Factors Influencing the Repair of Potentially Lethal Radiation Damage in Growth-Inhibited Human Cells

1973 • 131 citations

Potentially Lethal Radiation Damage: Repair by Mammalian Cells in Culture

1969 • 130 citations

The Action of Caffeine on X-Irradiated HeLa Cells. II. Synergistic Lethality

1977 • 129 citations

Potentially Lethal Damage versus Sublethal Damage: Independent Repair Processes in Actively Growing Chinese Hamster Cells

1979 • 129 citations

Repair of Sublethal and Potentially Lethal X-Ray Damage in Synchronous Chinese Hamster Cells

1972 • 125 citations

The action of caffeine on X-irradiated HeLa cells. I. Delayed inhibition of DNA synthesis.

1977 • 124 citations

DNA Double Strand Breaks in Ehrlich Ascites Tumour Cells at Low Doses of X-rays. I. Determination of Induced Breaks by Centrifugation at Reduced Speed

1982 • 123 citations

The British Journal of Cancer

1985 • 122 citations

Measurement of the Kinetics of DNA Double Strand Break Repair in Ehrlich Ascites Tumour Cells Using the Unwinding Method

1980 • 116 citations

Changes in Radiosensitivity and Dispersion of Chromatin during the Cell Cycle of Synchronous Chinese Hamster Cells

1972 • 112 citations

The combined effect of hydroxyurea and x-rays on Chinese hamster cells in vitro.

1968 • 109 citations

Cellular repair factors influencing radiocurability of human malignant tumours

1982 • 108 citations

The Repair of Potentially Lethal Damage in X-irradiated Cultures of Normal and Ataxia Telangiectasia Human Fibroblasts

1981 • 108 citations

Current Topics in Radiation Research

1971 • 106 citations

Effect of Confluent Holding on Potentially Lethal Damage Repair, Cell Cycle Progression, and Chromosomal Aberrations in Human Normal and Ataxia-Telangiectasia Fibroblasts

1985 • 104 citations

Current Topics in Radiation Research

1966 • 104 citations

Caffeine Enhancement of X-Ray Killing in Cultured Human and Rodent Cells

1978 • 103 citations

Sub-lethal and Lethal Radiation Damage

1967 • 101 citations

Enhancement of X-Ray Damage in Synchronous Chinese Hamster Cells by Hypertonic Treatments

1972 • 100 citations

Effects of 2-deoxy-D-glucose on glycolysis, proliferation kinetics and radiation response of human cancer cells

1985 • 99 citations

Effects of β-Arabinofuranosyladenine on the Growth and Repair of Potentially Lethal Damage in Ehrlich Ascites Tumor Cells

1980 • 99 citations

Dose-Rate Effects in Mammalian Cells: IV. Repairable and Nonrepairable Damage in Noncycling C3H 10T 1/2 Cells

1983 • 98 citations

The radiobiology of human neuroblastoma

1985 • 94 citations

The Action of Caffeine on X-Irradiated HeLa Cells. I. Delayed Inhibition of DNA Synthesis

1977 • 91 citations

Repair of potentially lethal lesions in x-irradiated, density-inhibited Chinese hamster cells: metabolic effects and hypoxia.

1973 • 86 citations

Repair of radiation damage in Lewis lung carcinoma cells following in situ treatment with fast neutrons and gamma-rays.

1975 • 86 citations

The shape of dose-survival curves for mammalian cells and repair of potentially lethal damage analyzed by hypertonic treatment.

1981 • 85 citations

Repair of potentially lethal damage in vivo in solid tumor cells after x-irradiation.

1974 • 84 citations

Ataxia-telangiectasia: a human mutation giving high-frequency misrepair of DNA double-stranded scissions.

1986 • 83 citations

Repair of Potentially Lethal Radiation Damage in Acute and Chronically Hypoxic Tumor Cellsin Vivo

1976 • 77 citations

Quantitative Aspects of Repair of Potentially Lethal Damage in Mammalian Cells

1979 • 74 citations

Effect of Radiomodifying Agents on the Ratios of X-ray-induced Lesions in Cellular DNA: Use in Lethal Lesion Determination

1985 • 72 citations

Repair of radiation damage to capillary endothelium

1975 • 71 citations

The effect of radiation on tumour growth delay, cell survival and cure of the animal using a single tumour system

1977 • 68 citations

The Action of Caffeine on X-Irradiated HeLa Cells. IV. Progression Delays and Enhanced Cell Killing at High Caffeine Concentrations

1980 • 66 citations

Influence of Temperature and Medium on the X-ray Sensitivities of Leukæmia Cells in vitro

1963 • 63 citations

The Effects of 9-β-D-arabinofuranosyladenine on the Repair of DNA Strand Breaks in X-irradiated Ehrlich Ascites Tumour Cells

1982 • 63 citations

Repair of Potentially-lethal Radiation Damage in Mammalian Cells: Enhancement by Conditioned Medium from Stationary Cultures

1971 • 61 citations

Hypothesis. Elkind recovery and “sub-lethal damage”: a misleading association?

1977 • 60 citations

Evidence That Repair and Expression of Potentially Lethal Damage Cause the Variations in Cell Survival after X Irradiation Observed through the Cell Cycle in Ehrlich Ascites Tumor Cells

1983 • 60 citations

Response of Human Osteosarcomain Vitroto Irradiation: Evidence for Unusual Cellular Repair Activity

1977 • 58 citations

Two Forms of Potentially Lethal Damage Have Similar Repair Kinetics in Plateau- and in Log-phase Cells

1985 • 57 citations

The survival of thyroid cells: in vivo irradiation and in situ repair.

1980 • 54 citations

The Shape of Dose-Survival Curves for Mammalian Cells and Repair of Potentially Lethal Damage Analyzed by Hypertonic Treatment

1981 • 54 citations

Independent Forms of Potentially Lethal Damage Fixed in Plateau-Phase Chinese Hamster Cells by Postirradiation Treatment in Hypertonic Salt Solution or araA

1985 • 54 citations

Studies on recovery processes in mouse L cells.

1967 • 54 citations

Radiation-Induced Cytogenetic Damage in Relation to Changes in Interphase Chromosome Conformation

1986 • 53 citations

Repair of Potentially Lethal Damage in X-Irradiated V79 Cells

1976 • 52 citations

Involvement of Poly (ADP-ribose) in the Radiation Response of Mammalian Cells

1984 • 52 citations

Modification of Recovery from Potentially Lethal X-Ray Damage in Plateau Phase Chinese Hamster Cells

1974 • 50 citations

Effects of X-radiation on Growth and Function of the Repair Blastema (Granulation Tissue)

1974 • 50 citations

Kinetics of Double Strand Break Repair in the DNA of X-irradiated Synchronized Mammalian Cells

1983 • 50 citations

Repair of Potentially Lethal Lesions in X-Irradiated, Density-Inhibited Chinese Hamster Cells: Metabolic Effects and Hypoxia

1973 • 50 citations

Rejoining of DNA double‐strand breaks in human fibroblasts and its impairment in one ataxia telangiectasia and two fanconi strains

1981 • 49 citations

Defective Recovery from Potentially Lethal Damage in Some Human Fibroblast Cell Strains

1983 • 48 citations

Split-dose Recovery Is Due to the Repair of DNA Double-strand Breaks

1984 • 47 citations

The Use of Recombinant DNA Techniques to Study Radiation-induced Damage, Repair and Genetic Change in Mammalian Cells

1986 • 47 citations

A Study of the Repair of Potentially Lethal and Sublethal Radiation Damage in Chinese Hamster Cells Exposed to Extremely Hypo- or Hypertonic NaCl Solutions

1979 • 47 citations

British journal of cancer

1980 • 45 citations

The Effect of Extreme Hypoxia and Glucose on the Repair of Potentially Lethal and Sublethal Radiation Damage by Mammalian Cells

1977 • 45 citations

The differential response of human tumours to fractionated radiation may be due to a post-irradiation repair process

1982 • 45 citations

Life-cycle Dependence of Repair of Potentially-lethal Radiation Damage

1973 • 45 citations

Characterization and Properties of Repair of Potentially Lethal Damage as Measured with the Help of β-Arabinofuranosyladenine in Plateau-Phase EAT Cells

1981 • 44 citations

Radiosensitivity and Repair of Radiation Damage in Human HF19 Fibroblasts

1980 • 44 citations

Evidence for the induction of two types of potentially lethal damage after exposure of plateau phase Chinese hamster V79 cells to?-rays

1985 • 42 citations

Modification of X-Ray-Induced Killing of HeLa S3 Cells by Inhibitors of DNA Synthesis

1967 • 41 citations

Repair of Radiation Damage as a Factor in Preoperative Radiation Therapy

2015 • 40 citations

Effects of Caffeine on X-irradiated Synchronous, Asynchronous and Plateau Phase Mouse Ascites Cells: The Importance of Progression Through the Cell Cycle for Caffeine Enhancement of Killing

1983 • 39 citations

Deficient Repair of Potentially Lethal Damage in Actively Growing Ataxia Telangiectasia Cells

1984 • 37 citations

Modification of the radiation induced damage by 2-deoxy-D-glucose in organ cultures of human cerebral gliomas

1987 • 37 citations

Fixation of Potentially Lethal Radiation Damage by Post-irradiation Exposure of Chinese Hamster Cells to 0·5 M or 1·5 M NaCl Solutions

1979 • 36 citations

Effects of Aphidicolin on Cell Proliferation, Repair of Potentially Lethal Damage and Repair of DNA Strand Breaks in Ehrlich Ascites Tumour Cells Exposed to X-rays

1982 • 36 citations

DNA repair in nondividing human lymphocytes: inhibition by deoxyadenosine.

1986 • 35 citations

Is cell survival a determinant of the in situ response of 9L tumours?

1980 • 35 citations

Radioresistant and repair proficient cells may determine radiocurability in human tumors

1986 • 35 citations

Potentially Lethal Damage

1979 • 35 citations

Lethal response of HeLa cells to x-irradiation in the latter part of the generation cycle

1976 • 35 citations

Response of cells of human origin, normal and malignant, to acute and low dose rate irradiation

1986 • 34 citations

CORRELATION OF CHROMOSOME DAMAGE AND COLONY-FORMING ABILITY IN SYRIAN HAMSTER CELLS IN CULTURE IRRADIATED IN G.

1972 • 34 citations

Enhanced Induction by X-irradiation of DNA Double-strand Breakage in Mitotic as Compared with S-phase V79 Cells

1986 • 34 citations

Hypoxic Fraction and Repair of Potentially Lethal Radiation Damage in Two Human Melanomas Transplanted into Nude Mice

1981 • 33 citations

Inhibition of X-Ray-Induced Potentially Lethal Damage (PLD) Repair by Cordycepin (3′-Deoxyadenosine) and Enhancement of Its Action by 2′-Deoxycoformycin in Chinese Hamster hai Cells in the Stationary Phase in Vitro

1980 • 33 citations

The Survival of Thyroid Cells: In Vivo Irradiation and in Situ Repair

1980 • 33 citations

Repair of potentially lethal damage in unfed plateau phase cultures of Ehrlich ascites tumour cells. II. Monolayer cultures.

1980 • 33 citations

Effects of the nucleoside analogues alpha-ara A, beta-ara A and beta-ara C on cell growth and repair of both potentially lethal damage and DNA double strand breaks in mammalian cells in culture.

1983 • 32 citations

Elkind recovery and “sub-lethal damage”: a misleading association?

1978 • 31 citations

Caffeine-Enhanced Survival of Radiation-Sensitive, Repair-Deficient Chinese Hamster Cells

1983 • 31 citations

Enhancement of Survival of CHO Cells by Acidic pH after X Irradiation

1982 • 31 citations

Effects of hypertonic sucrose on the radiosensitivity of Chinese hamster fibroblasts

1969 • 30 citations

Interpretation of the Shoulder of Dose—response Curves with Immediate Plating in Terms of Repair of Potentially Lethal Lesions During a Restricted time Period

1981 • 30 citations

Effect of Tonicity on Radiosensitivity of Mammalian Cells

1976 • 29 citations

An acidic extracellular environment reduces the fixation of radiation damage.

1984 • 28 citations

Repair of Potentially Lethal Damage Following Irradiation with X Rays or Cyclotron Neutrons: Response of the EMT-6/UW Tumor System Treated under Various Growth Conditions in Vitro and in Vivo

1981 • 28 citations

Repair of Radiation Damage in Plateau-phase Mammalian Cells: Relationship Between Sub-lethal and Potentially Lethal Damage States

1976 • 28 citations

Dose Fractionation Effects in Plateau-Phase Cultures of C3H 10T 1/2 Cells and Their Transformed Counterparts

1985 • 28 citations

The importance of G1/S-border and mitosis in the fixation of potentially lethal damage

1983 • 27 citations

Possible Importance of PLD Repair in the Modulation of BrdUrd and IdUrd-mediated Radiosensitization in Plateau-phase C3H10T1/2 Mouse Embryo Cells

1987 • 27 citations

The Effect of pH on Potentially Lethal Damage Recovery in A549 Cells

1986 • 27 citations

The Effect of Hypertonic Shock on the Radiation Response of HeLa-3 Cells

1972 • 26 citations

Discrepancies between Patterns of Potentially Lethal Damage Repair in the RIF-1 Tumor System in Vitro and in Vivo

1983 • 26 citations

Alterations in the Radiosensitivity of CHO Cells by Anisotonic Treatments: Correlations between Cell Lethality and Chromosomal Aberrations

1979 • 26 citations

Fixation of Potentially Lethal Radiation Damage in Chinese Hamster Cells by Anisotonic Solutions, Polyamines, and DMSO

1981 • 26 citations

The Influence of Post-irradiation Conditions on the Survival of Chinese Hamster Cells after Gamma-irradiation

1970 • 26 citations

Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains.

1984 • 26 citations

Potentially lethal damage repair as a possible determinant of human tumour radiosensitivity

1984 • 26 citations

Purine Nucleoside Analogues Inhibit the Repair of Radiation-induced Potentially Lethal Damage in Mammalian Cells in Culture

1982 • 26 citations

Induction of Chromosome Aberrations and Cell Killing in Syrian Hamster Fibroblasts by γ-rays, X-rays and Fast Neutrons

1985 • 25 citations

Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage.

1982 • 25 citations

Relationship between the repair of radiation-induced DNA damage and recovery from potentially lethal damage in 9L rat brain tumor cells.

1984 • 25 citations

The survival of parenchymal hepatocytes irradiated with low and high LET radiation.

1984 • 24 citations

The Action of Caffeine on X-Irradiated HeLa Cells: V. Identity of the Sector of Cells That Expresses Potentially Lethal Damage in G 1 and G 2

1982 • 24 citations

Correlation of Survival with the Restoration of DNA Structure in X-Irradiated L5178Y S/S Cells

1980 • 24 citations

The role of dna repair processes in the response of human tumors to fractionated radiotherapy

1984 • 23 citations

The Action of Caffeine on X-Irradiated HeLa Cells: VIII. Recovery from Potentially Lethal Damage

1986 • 22 citations

Conditioned Medium from Plateau-Phase Cells

1975 • 22 citations

Effect of Salt Solutions on Radiosensitivity of Mammalian Cells

1977 • 22 citations

Optimization of cancer therapy: Part I--Inhibition of repair of x-ray induced potentially lethal damage by 2-deoxy-D-glucose in Ehrlich-ascites tumour cells.

1977 • 22 citations

The Effects of Caffeine on the Expression of Potentially Lethal and Sublethal Damage in γ-Irradiated Cultured Mammalian Cells

1979 • 22 citations

An Acidic Extracellular Environment Reduces the Fixation of Radiation Damage

1984 • 22 citations

Effect of Salt Solutions on Radiosensitivity of Mammalian Cells

1977 • 22 citations

Changes in Repair of Potentially Lethal Damage with Culture Age in EMT6 Cells

1979 • 21 citations

Radiation-Induced Giant Cell Formation: The Influence of Conditions Which Enhance Repair of Potentially Lethal Damage

1976 • 21 citations

Effect of Membrane Lipid Perturbers on the Temperature Dependence of Repair of Sublethal and Potentially Lethal Radiation Damage

1981 • 21 citations

Dose-rate effects in mammalian cells: V. dose fractionation effects in noncycling c3h cells

1984 • 20 citations

Rapid Recovery in Plateau-Phase Mammalian Cells

1979 • 20 citations

Chromosome condensation may enhance X-ray-related cell lethality in a temperature-sensitive mutant (tsBN2) of baby hamster kidney cells (BHK21).

1987 • 20 citations

Factors influencing the recovery from potentially lethal damage (PLD) in mammalian cells in vitro and in vivo

1980 • 20 citations

Evidence for Reduced Capacity for Damage Accumulation and Repair in Plateau-Phase C3H 10T 1/2 Cells Following Multiple-Dose Irradiation with γ Rays

1986 • 20 citations

Reduced Repair of Potentially Lethal Radiation Damage in Glutathione Synthetase-deficient Human Fibroblasts after X-irradiation

1985 • 19 citations

Repair and fixation of potentially lethal damage (PLD) as demonstrated by delayed plating or incubation with araA in contact inhibited refed plateau-phase C3H mouse embryo 10 T1/2 cells grown in the presence of BrdUrd

1987 • 19 citations

Loss of Repair Capacity in Density-Inhibited Cultures of C3H 10T 1/2 Cells during Multifraction Irradiation

1985 • 19 citations

Potentially Lethal Damage Repair in Cell Lines of Radioresistant Human Tumours and Normal Skin Fibroblasts

1985 • 19 citations

Survival of parenchymal hepatocytes irradiated with 14.3 MeV neutrons

1984 • 19 citations

Prematurely condensed chromosomes: a model system for visualizing effects of DNA damage, repair and inhibition at the level of chromosome structure.

1984 • 18 citations

Aphidicolin promotes repair of potentially lethal damage in irradiated mammalian cells synchronized in S-phase

1982 • 18 citations

Fixation and Repair of Radiation Damage in Normal and Ataxia-telangiectasia Human Cells

1984 • 18 citations

The Action of Caffeine on X-Irradiated HeLa Cells: VI. Damping of the Structured Age-Survival Function

1984 • 18 citations

Radiobiological studies of tumours in situ compared with cell survival.

1980 • 18 citations

RECOVERY FROM RADIATION DAMAGE IN MAMMALIAN CELLS.

1971 • 18 citations

Effect of Anisotonic NaCl Treatment on Cellular Ultrastructure of V79 Chinese Hamster Cells. Part 1 Mitotic Cells

1983 • 16 citations

Repair of Potentially Lethal Damage in Unfed Plateau Phase Cultures of Ehrlich Ascites Tumour Cells II. Monolayer Cultures

1980 • 16 citations

Ataxia-Telangiectasia Homo- and Heterozygous Cells Show a Normal Repair and Fixation Response to Anisotonic NaCl Treatment after Irradiation

1985 • 16 citations

Effects of ara A and fresh medium on chromosome damage and DNA double-strand break repair in X-irradiated stationary cells.

1984 • 16 citations

Radiosensitivity of nall human melanoma transplanted into nude mice: Repair, reoxygenation and dose fractionation

1982 • 15 citations

The influence of in situ repair systems on survival of several irradiated parenchymal cell types.

1984 • 15 citations

Enhancement of Survival of Irradiated Plateau Phase Cells by Dinitrophenol: Effect of Dose-Rate and Cell Strain

1976 • 15 citations

Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus

1980 • 15 citations

Repair of Potentially Lethal Radiation Damage in Confluent and Non-confluent Cultures of Human Hybrid Cells

1985 • 14 citations

Repair of Potentially Lethal X-ray Damage in Fibroblasts Derived from Patients with Hereditary and D-deletion Retinoblastoma

1985 • 14 citations

Repair following combined X-ray and heat at 41 degrees in plateau-phase mammalian cells.

1977 • 13 citations

The role in cancer therapy of inhibiting recovery from PLD induced by radiation or bleomycin

1984 • 13 citations

9-β-D-Arabinofuranosyladenine Increases the Frequency of X-ray Induced Chromosome Abnormalities in Mammalian Cells

1983 • 13 citations

In SituRecovery from Potentially Lethal Damage after Irradiation with BEVALAC Accelerated Carbon Ions

1980 • 13 citations

Arrest of Irradiated G1, S, or G2 Cells at Mitosis Using Nocodazole Promotes Repair of Potentially Lethal Damage

1984 • 12 citations

PLD repair in rat rhabdomyosarcoma tumor cells irradiated in vivo and in vitro with high-LET and low-LET radiation.

1986 • 12 citations

Effects of nutritional state on the expression of radiation injury in two tumor subpopulations obtained from a heterogeneous human colon carcinoma

1986 • 12 citations

Modifications in Repair and Expression of Potentially Lethal Damage (α-PLD) as Measured by Delayed Plating or Treatment with β-araA in Plateau-Phase Ehrlich Ascites Tumor Cells after Exposure to Charged Particles of Various Specific Energies

1987 • 12 citations

Evidence for the repair of potentially lethal damage in irradiated bone marrow

1982 • 12 citations

The chemical inhibition of PLDR (potentially lethal damage repair) in vitro and in vivo in cancer therapy

1982 • 12 citations

Effect of Salt Solutions on the Radiosensitivity of Mammalian Cells

1978 • 12 citations

Survival of Synchronized V79 Cells Treated with X-rays and Cordycepin

1977 • 12 citations

The relationship between lung colony and in situ assays

1985 • 11 citations

Potentially Lethal Damage, Deficient Repair in X-Ray-Sensitive Caffeine-Responsive Chinese Hamster Cells

1986 • 11 citations

Survival and repair of potentially lethal radiation damage in confluent vascular smooth muscle cell cultures

1986 • 11 citations

Potentially Lethal Damage Repair (PLDR) in X-irradiated Cultures of a Normal Human Diploid Fibroblast Cell Strain

1983 • 11 citations

Effects of LET∞ on the Fate of DNA Damage Induced in Rabbit Sensory Cells In Situ: Fundamental Aspects

1986 • 11 citations

Encapsulated iodine-125 in radiation oncology. II. Study of the dose rate effect on potentially lethal damage repair (PLDR) using mammalian cell cultures in plateau phase.

1984 • 11 citations

In vitro effects of N,N-dimethylformamide on sublethal and potentially lethal damage recovery processes after X-irradiation in heterogeneous human colon tumor cells.

1985 • 11 citations

Relationship between DNA repair and cell recovery: Importance of competing biochemical and metabolic processes

1985 • 11 citations

Chromosome Condensation May Enhance X-Ray-Related Cell Lethality in a Temperature-Sensitive Mutant (tsBN2) of Baby Hamster Kidney Cells (BHK21)

1987 • 11 citations

Recovery from potentially lethal damage following irradiation with x-rays or cyclotron neutrons—I Response of emt-6 cells in vitrot

1978 • 10 citations

Effect of hypoxia on recovery from damage induced by heat and radiation in plateau-phase CHO cells.

1985 • 10 citations

Repair of sublethal and potentially lethal damage in lung cells using anin vitrocolony method

1981 • 9 citations

Relative Responses of an X-ray-resistant Hybrid Cell-line and Its Parent Line to X-irradiation, Ultraviolet Light, Actinomycin D and Cordycepin

1977 • 9 citations

Effects of adenosine deaminase inhibitor 2?-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to?-areaA

1985 • 9 citations

Response of selected tumour cell populations separated from a fibrosarcoma following irradiationin situwith fast neutrons

1978 • 9 citations

Encapsulated iodine-125 in radiation oncology

1984 • 9 citations

Enhancement of Radiation Killing of Cultured Mammalian Cells by Cordycepin

1978 • 9 citations

Evidence for Similarities between Radiation Damage Expressed by β-araA and Damage Involved in the Interaction Effect Observed after Exposure of V79 Cells to Mixed Neutrons and γ Radiation

1985 • 8 citations

Enhancement of X-ray induced potentially lethal damage by low temperature storage of mammalian cells

1977 • 8 citations

Recovery following potentially-lethal damage in chinese hamster cells (v-79) in plateauphase cultures and in mouse mammary adenocarcinoma cells (mtg-b) in vitro and in vivo. Abstr.

1975 • 8 citations

Evidence for Differences among the Sectors of Potentially Lethal Damage Expressed by Hypertonic Treatment in Plateau-Phase V79 Cells after Exposure to Neutrons or γ Rays: The Importance of Distinction between α and β-PLD Forms

1986 • 8 citations

Effects of aphidicolin on the repair and fixation of potentially lethal damage sensitive to β-araA

1985 • 8 citations

PLD Repair in Rat Rhabdomyosarcoma Tumor Cells Irradiated in Vivo and in Vitro with High-LET and Low-LET Radiation

1986 • 8 citations

Effect of Hypoxia on Recovery from Damage Induced by Heat and Radiation in Plateau-Phase CHO Cells

1985 • 7 citations

The Kinetics ofin SituRepair in Rat Mammary Cells

1983 • 7 citations

The effect of recovery from potentially lethal damage on the determination of reoxygenation in a murine tumour

1979 • 7 citations

Repair of Sublethal and Potentially Lethal Damage in Mouse Kidney Cellsin SituUsing anin VitroColony Method

1982 • 6 citations

Combined use of bleomycin in radiotherapy of a mouse mammary carcinoma.

1976 • 6 citations

Inhibition of recovery from potentially lethal damage by chemicals in Chinese hamster V79 A cells

1985 • 5 citations

The Repair of Potentially Lethal and Sublethal Damage in Unfed Plateau-Phase Cultures Irradiated at 0.78 Gy/hr

1982 • 5 citations

Split-dose recovery explained quantitatively by repair of potentially lethal lesions.

1984 • 4 citations

The effect of recovery from potentially lethal damage on the determination of repair and repopulation in a murine tumour

1985 • 3 citations

Time-lapse Microscopy of Chinese Hamster Cells under Conditions of PLD Repair and Non-PLD Repair after Irradiation

1985 • 2 citations

Molecular biology in medicine

1977 • 1 citations

Device of anoxic chamber system and repair of potentially lethal damage of anoxic cells in vitro.

1986 • 1 citations