Natural History of β-Cell Autoimmunity in Young Children with Increased Genetic Susceptibility to Type 1 Diabetes Recruited from the General Population

Measuring the Accuracy of Diagnostic Systems

1988 • 9,129 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Prediction of Type I Diabetes in First-Degree Relatives Using a Combination of Insulin, GAD, and ICA512bdc/IA-2 Autoantibodies

1996 • 788 citations

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study.

1999 • 633 citations

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes

2000 • 456 citations

Prediction of IDDM in the General Population: Strategies Based on Combinations of Autoantibody Markers

1997 • 425 citations

Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort

2001 • 336 citations

Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group.

1998 • 283 citations

A Novel Micro-assay for Insulin Autoantibodies

1997 • 238 citations

The First Signs of β-Cell Autoimmunity Appear in Infancy in Genetically Susceptible Children from the General Population: The Finnish Type 1 Diabetes Prediction and Prevention Study

2001 • 215 citations

IA-2 antibodies - a sensitive marker of IDDM with clinical onset in childhood and adolescence

1998 • 182 citations

Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity

1995 • 178 citations

Triple-label hybridization assay for type-1 diabetes-related HLA alleles.

1995 • 169 citations

Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

1998 • 157 citations

Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: results of the Fourth International Workshop on the Standardization of Insulin Autoantibody Measurement.

1992 • 147 citations

Early Environmental Events as a Cause of IDDM: Evidence and Implications

1994 • 147 citations

Rapid HLA-DQB1 Genotyping for Four Alleles in the Assessment of Risk for IDDM in the Finnish Population

1996 • 138 citations

Early Autoantibody Responses in Prediabetes Are IgG1 Dominated and Suggest Antigen-Specific Regulation

1999 • 131 citations

Genetic markers, humoral autoimmunity, and prediction of type 1 diabetes in siblings of affected children. Childhood Diabetes in Finland Study Group.

2000 • 97 citations

Islet autoimmunity in infants with a Type I diabetic relative is common but is frequently restricted to one autoantibody

2000 • 82 citations

Islet Cell Antibodies as Predictive Markers for IDDM in Children With High Background Incidence of Disease

1990 • 72 citations

Transient Antiislet Autoantibodies: Infrequent Occurrence and Lack of Association with “Genetic” Risk Factors¹

2000 • 60 citations

Costs of predicting IDDM

1998 • 53 citations

Postnatal Elimination of Transplacentally Acquired Disease-Associated Antibodies in Infants Born to Families with Type 1 Diabetes¹

2000 • 51 citations

Disease-Associated Autoantibodies as Surrogate Markers of Type 1 Diabetes in Young Children at Increased Genetic Risk¹

2000 • 49 citations

Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum

2001 • 46 citations

Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren

2000 • 27 citations

Immunogenetic Determinants and Prediction of IDDM in French Schoolchildren

1995 • 26 citations

IDDM prevention trials in progress--a critical assessment.

1998 • 20 citations

Perspectives in Diabetes Early Environmental Events as a Cause of IDDM Evidence and Implications

1994 • 6 citations