Cytokine and chemokine production in HSV-1 latently infected trigeminal ganglion cell cultures: Effects of hyperthermic stress

Chemokines

1997 • 1,926 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Tumor necrosis factor identified in multiple sclerosis brain.

1989 • 793 citations

Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus.

1989 • 785 citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1989 • 692 citations

Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production

1991 • 579 citations

The Immune Response Evokes Changes in Brain Noradrenergic Neurons

1983 • 442 citations

Differential CC chemokine-induced enhancement of T helper cell cytokine production.

1997 • 417 citations

Expression of chemokine receptors by subsets of neurons in the central nervous system.

1997 • 384 citations

Nervous tissue as an immune compartment: the dialect of the immune response in the CNS

1994 • 366 citations

Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma.

1996 • 321 citations

Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro.

1996 • 316 citations

Induction and regulation of interleukin-6 gene expression in rat astrocytes

1990 • 314 citations

Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain.

1996 • 311 citations

Activation of NK cells by CC chemokines. Chemotaxis, Ca2+ mobilization, and enzyme release.

1996 • 284 citations

Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection

1996 • 266 citations

A monoclonal antibody specific for mouse dendritic cells.

1982 • 249 citations

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients.

1988 • 246 citations

Different Roles for L3T4+ and Lyt 2+ T Cell Subsets in the Control of an Acute Herpes Simplex Virus Infection of the Skin and Nervous System

1987 • 236 citations

Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1

1995 • 231 citations

Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1.

1996 • 229 citations

Neutrophil-mediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea

1996 • 222 citations

Chemokine gene expression in the brains of mice with lymphocytic choriomeningitis

1997 • 192 citations

Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration

1997 • 175 citations

Interleukin-6 mRNA expression by cortical neurons in culture: Evidence for neuronal sources of interleukin-6 production in the brain

1995 • 160 citations

Maintenance of Latent Herpetic Infection: An Apparent Role for Anti-Viral IgG

1974 • 154 citations

Mechanisms of herpes simplex virus type 1 reactivation

1996 • 152 citations

Immune cell infiltration and persistence in the mouse trigeminal ganglion after infection of the cornea with herpes simplex virus type 1

1995 • 150 citations

Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis

1990 • 149 citations

Differential effects of hyperthermia on macrophage interleukin-6 and tumor necrosis factor-alpha expression

1994 • 148 citations

Regulation of IL 3 expression by glucocorticoids in cloned murine T lymphocytes.

1985 • 147 citations

A Sensitive Elisa for the Detection of Human Monocyte Chemoattractant Protein-1 (MCP-1)

1992 • 142 citations

Characterization of herpes simplex virus type-1 infection and herpetic stromal keratitis development in IFN-gamma knockout mice.

1995 • 139 citations

Production of Peptide Hormones and Neurotransmitters by the Immune System

1997 • 127 citations

Human gamma interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus

1989 • 126 citations

Interleukin-10 treatment can suppress stromal keratitis induced by herpes simplex virus type 1.

1994 • 123 citations

Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection.

1996 • 118 citations

Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection

1996 • 115 citations

Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex

1995 • 113 citations

Neonatal herpes simplex virus infections

1993 • 109 citations

Endogenously produced interferon protects mice from herpes simplex virus type 1 corneal disease

1991 • 108 citations

Stress Downregulates Lipopolysaccharide-Induced Expression of Proinflammatory Cytokines in the Spleen, Pituitary, and Brain of Mice

1995 • 105 citations

Modulation of acute and latent herpes simplex virus infection in C57BL/6 mice by adoptive transfer of immune lymphocytes with cytolytic activity

1989 • 101 citations

Cytokine expression by human peripheral blood dendritic cells stimulated in vitro with HIV-1 and herpes simplex virus.

1996 • 94 citations

Cytokine expression in vivo during murine herpetic stromal keratitis. Effect of protective antibody therapy.

1993 • 94 citations

Latency of Herpes Simplex Virus in Absence of Neutralizing Antibody: Model for Reactivation

1980 • 85 citations

Exacerbation of murine herpes simplex virus-mediated stromal keratitis by Th2 type T cells.

1993 • 72 citations

Role of hsp70 in cytokine production

1994 • 70 citations

Production of Peptide Hormones and Neurotransmitters by the Immune System

1992 • 67 citations

Viral, neuronal and immune factors which may influence herpes simplex virus (HSV) latency and reactivation

1993 • 65 citations

Innate and Acquired Immunity to Herpes Simplex Virus Type 1

1997 • 63 citations

Cell-mediated immunity and immunosuppression in herpes simplex virus infection.

1993 • 58 citations

Production and Characterization of Human Glioma Cell-Derived Monocyte Chemotactic Factor

1989 • 42 citations

Synergistic anti-HSV effect of tumor necrosis factor alpha and interferon gamma in human corneal fibroblasts is associated with interferon beta induction

1993 • 36 citations

Heat shock-induced reactivation of herpes simplex virus type 1 in latently infected mouse trigeminal ganglion cells in dissociated culture

1994 • 31 citations

Molecular cloning of the coding sequence of an interleukin-2 receptor α subunit cDNA in murine brain

1995 • 18 citations