Sustained Elevated Levels of VCAM-1 in Cultured Fibroblast-like Synoviocytes Can Be Achieved by TNF-α in Combination with Either IL-4 or IL-13 through Increased mRNA Stability

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

1996 • 602 citations

Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.

1994 • 478 citations

Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1).

1992 • 476 citations

Functional analysis of the human vascular cell adhesion molecule 1 promoter.

1992 • 442 citations

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

1995 • 424 citations

NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation.

1994 • 416 citations

Endothelial Interferon Regulatory Factor 1 Cooperates with NF-κB as a Transcriptional Activator of Vascular Cell Adhesion Molecule 1

1995 • 301 citations

Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?

1993 • 272 citations

Involvement of nuclear factor kB in the regulation of cyclooxygenase‐2 expression by interleukin‐1 in rheumatoid synoviocytes

1997 • 252 citations

The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent.

1994 • 250 citations

Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells.

1995 • 235 citations

Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes.

1992 • 202 citations

Comparison of immunohistochemistry and RT‐PCR for detection of CD44v‐expression, a new prognostic factor in human breast cancer

1995 • 150 citations

Expression of vascular cell adhesion molecule-1 in normal and inflamed synovium.

1993 • 131 citations

Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).

1991 • 124 citations

Cell contact between T cells and synovial fibroblasts causes induction of adhesion molecules and cytokines

1993 • 112 citations

TNF-alpha and IL-4 synergistically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells.

1997 • 108 citations

The presence of interleukin‐13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritis

1996 • 99 citations

Expression of vascular cell adhesion molecule-1 mRNA and protein in rheumatoid synovium demonstrated by in situ hybridization and immunohistochemistry.

1995 • 85 citations

Expression of vascular cell adhesion molecule-1 in fibroblastlike synoviocytes after stimulation with tumor necrosis factor.

1992 • 85 citations

Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor

1996 • 81 citations

Postinduction transcriptional repression of E-selectin and vascular cell adhesion molecule-1.

1996 • 46 citations

Differential expression in rheumatoid synovium and synovial fluid of alpha 4 beta 7 integrin. A novel receptor for fibronectin and vascular cell adhesion molecule-1.

1993 • 44 citations

Cell adhesion molecules in rheumatoid arthritis

1995 • 44 citations

ROLE OF ADHESION MOLECULES IN THE PATHOGENESIS OF RHEUMATOID ARTHRITIS

1995 • 42 citations

Expression of functional VCAM-1 by cultured nasal polyp-derived microvascular endothelium.

1997 • 42 citations

Interacting monocytes and synoviocytes induce adhesion molecules by a cytokine-regulated process.

1993 • 40 citations

Tumor Necrosis Factor α Enhances the Expression of the Interleukin (IL)-4 Receptor α-Chain on Endothelial Cells Increasing IL-4 or IL-13-induced Stat6 Activation

1997 • 40 citations

Interleukin‐4 induces endothelial vascular cell adhesion molecule‐1 (VCAM‐1) by an NF‐κb‐independent mechanism

1995 • 32 citations

Co-culture of synovial fibroblasts and differentiated U937 cells is sufficient for high interleukin-6 but not interleukin-1beta or tumour necrosis factor-alpha release

1998 • 20 citations