The enzymology of stimulated inositol lipid turnover

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

The Thyroid Gland.

1965 • 1,816 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

Form and function of phospholipids

1973 • 1,072 citations

Intracellular phospholipases A

1980 • 989 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

The Golgi Apparatus: Two Organelles in Tandem

1981 • 438 citations

Inositol phospholipids in membrane function

1979 • 272 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

Relationship between hormonal activation of phosphatidylinositol hydrolysis, fluid secretion and calcium flux in the blowfly salivary gland

1979 • 193 citations

Purification of phosphatidylinositol-specific phospholipase C from rat liver.

1981 • 180 citations

Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation

1980 • 178 citations

A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, <scp>d</scp>-myoinositol 1:2-cyclic phosphate and <scp>d</scp>-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex

1973 • 141 citations

The phosphatidylinositol kinase of rat brain

1966 • 138 citations

Phosphoinositides. 3. Enzymic hydrolysis of inositol-containing phospholipids

1961 • 137 citations

Dynamic Aspects of Phospholipids during Protein Secretion

1968 • 137 citations

Origin of the latency phase during the action of phospholipase A2 on unmodified phosphatidylcholine vesicles

1982 • 134 citations

Properties of phospholipase C isolated from rat liver lysosomes.

1980 • 128 citations

The diphosphoinositide kinase of rat brain

1968 • 128 citations

Phosphatidylinositol specific phospholipases C

1982 • 112 citations

The activation of phosphatidylinositol-hydrolyzing phospholipase A2 during prostaglandin synthesis in transformed mouse BALB/3T3 cells.

1981 • 104 citations

Studies on the enzymic hydrolysis of monophosphoinositide by phospholipase preparations from P. notatum and ox pancreas

1959 • 102 citations

The properties and subcellular distribution of phosphatidylinositol kinase in mammalian tissues

1969 • 99 citations

The triphosphoinositide phosphodiesterase of brain tissue

1964 • 99 citations

The Calcium‐Dependent Phosphatidylinositol‐Phosphodiesterase of Rat Brain

1979 • 92 citations

Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane

1967 • 91 citations

THE DISTRIBUTION OF CALCIUM‐DEPENDENT PHOSPHATIDYLINOSITOL‐SPECIFIC PHOSPHODIESTERASE IN RAT BRAIN

1978 • 90 citations

The triphosphoinositide phosphomonoesterase of brain tissue

1964 • 84 citations

The control by Ca2+ of the polyphosphoinositide phosphodiesterase and the Ca2+-pump ATPase in human erythrocytes

1982 • 80 citations

Phosphatidylinositol cleavage in lymphocytes. Requirement for calcium ions at a low concentration and effects of other cations

1974 • 77 citations

Specificity of phospholipases in methylcholanthrene-transformed mouse fibroblasts activated by bradykinin, thrombin, serum, and ionophore A23187.

1979 • 75 citations

Soluble and particulate forms of phosphoinositide phosphodiesterase in ox brain

1972 • 71 citations

The hydrolysis of phosphatidylinositol monolayers at an air/water interface by the calcium-ion-dependent phosphatidylinositol phosphodiesterase of pig brain

1981 • 71 citations

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0

1974 • 70 citations

The hydrolysis of triphosphoinositide by extracts of ox brain

1964 • 69 citations

The role of calcium in regulation of cyclic nucleotide content in human umbilical artery.

1975 • 66 citations

METABOLISM OF THE PHOSPHOINOSITIDES IN GUINEA-PIG BRAIN SYNAPTOSOMES

1969 • 65 citations

TRIPHOSPHOINOSITIDE PHOSPHOMONOESTERASE ACTIVITY IN NERVE CELL BODIES, NEUROGLIA AND SUBCELLULAR FRACTIONS FROM WHOLE RAT BRAIN

1967 • 55 citations

Studies on the properties of triphosphoinositide phosphomonoesterase and phosphodiesterase of rabbit iris smooth muscle

1978 • 54 citations

The Inhibition and Activation of Ca²⁺‐Dependent Phosphatidylinositol Phosphodiesterase by Phospholipids and Blood Plasma

1980 • 51 citations

Hydrolysis of membrane phospholipids by phospholipases of rat liver lysosomes

1979 • 49 citations

Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain

1982 • 48 citations

Polyphosphoinositide biosynthesis in three subfractions of rat brain myelin

1978 • 46 citations

Localization of enzymes involve in polyphosphoinositide metabolism on the cytoplasmic surface of the human erythrocyte membrane

1975 • 46 citations

Human erythrocyte cytosol phosphatidyl-inositol-bisphosphate phosphatase

1981 • 43 citations

Studies on the properties of a soluble phosphatidylinositol-phosphodiesterase of rabbit iris smooth muscle

1980 • 42 citations

Purification and properties of polyphosphoinositide phosphomonoesterase from rat brain

1977 • 41 citations

THE ENZYMIC HYDROLYSIS OF PHOSPHATIDYL INOSITOL BY GUINEA PIG BRAIN:

1969 • 41 citations

Phosphomonoesterase hydrolysis of polyphosphoinositides in rat kidney: Properties and subcellular localization of the enzyme system

1975 • 38 citations

Proteolytic activation can produce a phosphatidylinositol phosphodiesterase highly sensitive to Ca2+

1982 • 35 citations

The subcellular distribution of triphosphoinositide phosphomonoesterase in guinea-pig brain

1972 • 35 citations

Biosynthesis of triphosphoinositide in rat kidney cortex

1970 • 34 citations

The acylation of lysophosphatidylcholine by subcellular fractions of guinea-pig cerebral cortex

1980 • 30 citations

Phospholipase activities of rat brain cytosol occurrence of phospholipase c activity with phosphatidylcholine

1982 • 29 citations

Rapid Incorporation In Vivo of Intracerebrally Injected ³²Pi into Polyphosphoinositides of Three Subfractions of Rat Brain Myelin

1981 • 29 citations

Phosphatidylinositol kinase in rat kidney cortex

1969 • 27 citations

Stimulated Phosphatidylinositol Turnover A Brief Appraisal

1982 • 26 citations

The structures of enzymically produced diphosphoinositide and triphosphoinositide

1968 • 25 citations

Heterogeneity of the calcium-dependent phosphatidylinositol-phosphodiesterase of rat liver and kidney, as revealed by column chromatofocusing

1982 • 20 citations

Cyclic AMP-dependent diphosphoinositide kinase☆

1972 • 19 citations

Degradation of phosphatidylinositol by soluble enzymes of rat gastric mucosa

1981 • 16 citations

THE BIOSYNTHESIS OF TRIPHOSPHOINOSITIDE BY PURIFIED MYELIN OF PERIPHERAL NERVE

1969 • 16 citations

Endogenous lipolytic activities during autolysis of highly enriched hepatic lysosomes

1981 • 13 citations

The mechanism and function of phosphatidylinositol turnover

1980 • 12 citations

Phosphatidylinositol-hydrolysing enzymes in blowfly salivary glands

1982 • 11 citations