Facilitated Transport of the Neurotoxin, β‐N‐Methylamino‐<scp>l</scp>‐Alanine, Across the Blood‐Brain Barrier

Partition coefficients and their uses

1971 • 4,444 citations

Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

1971 • 1,671 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

Amino acid assignment to one of three blood-brain barrier amino acid carriers

1976 • 593 citations

An in situ brain perfusion technique to study cerebrovascular transport in the rat

1984 • 538 citations

Kinetics of Neutral Amino Acid Transport Across the Blood‐Brain Barrier

1987 • 441 citations

Human motor neuron diseases.

1982 • 352 citations

Application of 31P-NMR spectroscopy to the study of striated muscle metabolism

1982 • 306 citations

The transport of cationic amino acids across the plasma membrane of mammalian cells

1985 • 287 citations

Organic ion transport during seven decades the amino acids

1984 • 284 citations

Toxicity of cycads

1963 • 275 citations

Disappearance of high‐incidence amyotrophic lateral sclerosis and parkinsonism‐dementia on Guam

1985 • 217 citations

Neurotoxicity ofβ-N-methylamino-l-alanine (BMAA) andβ-N-oxalylamino-l-alamine (BOAA) on cultured cortical neurons

1989 • 206 citations

Beta- N -Methylamino-L-Alanine Neurotoxicity: Requirement for Bicarbonate as a Cofactor

1988 • 199 citations

Neutral amino acid transport at the human blood-brain barrier.

1988 • 191 citations

2‐Amino‐3‐(methylamino)‐propanoic acid (BMAA) in cycad flour

1990 • 187 citations

Specific antagonism of excitotoxic action of ‘uncommon’ amino acids assayed in organotypic mouse cortical cultures

1987 • 154 citations

Amyotrophic lateral sclerosis and parkinson's disease complex on Guam linked to an environmental neurotoxin

1988 • 148 citations

Neurodegenerative disorders of the western pacific: the search for mechanisms of pathogenesis

1986 • 134 citations

Guam ALS/Parkinsonism-Dementia: A Long-Latency Neurotoxic Disorder Caused by “Slow Toxin(s)” in Food?

1987 • 131 citations

Regional Blood‐Brain Barrier Permeability to Amino Acids After Portacaval Anastomosis

1982 • 118 citations

Interrelationships between level of amino acids in plasma and tissues during starvation

1971 • 108 citations

The preparation of l- and d-α-amino-β-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the l-isomer

1968 • 105 citations

Transport of Diamino Acids into the Ehrlich Cell

1966 • 105 citations

2-amino-3-(methylamino)-propanoic acid (BMAA) pharmacokinetics and blood-brain barrier permeability in the rat.

1991 • 94 citations

The interaction of β‐N‐methylamino‐L‐alanine with bicarbonate: an ¹H‐NMR study

1989 • 82 citations

Selective degeneration of cerebellar cortical neurons caused by cycad neurotoxin, L‐β‐methylaminoalanine (L‐BMAA), in rats

1990 • 75 citations

Neuroactive carbamate adducts of beta-N-methylamino-L-alanine and ethylenediamine. Detection and quantitation under physiological conditions by 13C NMR.

1990 • 74 citations

Measurement of correlation of partition coefficients of polar amino acids.

1981 • 70 citations

The Effect of Age upon the Entry of Some Amino Acids into the Brain, and their Incorporation into Cerebral Protein

1978 • 65 citations

12. Studies On Cycasin, a New Toxic Glycoside, of Cycas revoluta Thunb

1955 • 58 citations

Amino acid supply to individual cerebral structures in awake and anesthetized rats

1982 • 54 citations

L-methionine uptake by human cerebral cortex: maturation from infancy to old age.

1991 • 54 citations

Evidence for an Alanine, Serine, and Cysteine System of Transport in Isolated Brain Capillaries

1987 • 53 citations

Regional Cerebrovascular Transport of Leucine as Measured by the in situ Brain Perfusion Technique

1985 • 52 citations

AMYOTROPHIC LATERAL SCLEROSIS AND PARKINSONISM-DEMENTIA ON GUAM: A 25-YEAR PROSPECTIVE CASE-CONTROL STUDY

1986 • 50 citations

Quantification of the Putative Neurotoxin 2-Amino-3-(methylamino)propanoic Acid (BMAA) in Cycadales: Analysis of the Seeds of Some Members of the Family Cycadaceae

1989 • 45 citations

The Blood-Brain Barrier and the Regulation of Amino Acid Uptake and Availability to Brain

1991 • 43 citations

Some Characteristics of Threonine Transport Across the Blood‐Brain Barrier of the Rat

1988 • 34 citations

a1-Antitrypsin Types in Schizophrenia

1985 • 33 citations

pH Dependence of Histidine Affinity for Blood‐Brain Barrier Carrier Transport Systems for Neutral and Cationic Amino Acids

1988 • 20 citations

Factors Determining the Preservation of Protein Status during Dietary Protein Deprivation

1981 • 19 citations