The transport of cationic amino acids across the plasma membrane of mammalian cells

Untersuchungen uber die Harnstoffbildung im Tierkörper

1932 • 3,104 citations

Data for biochemical research

1987 • 3,056 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

[6] Statistical analysis of enzyme kinetic data

1979 • 2,002 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

Distinct Mediating Systems for the Transport of Neutral Amino Acids by the Ehrlich Cell

1963 • 839 citations

Metabolic Control and Disease.

1980 • 570 citations

The regulation of amino acid transport in animal cells

1978 • 467 citations

The regulation of neutral amino acid transport in mammalian cells

1983 • 459 citations

Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.

1980 • 429 citations

A Distinct Na+-requiring Transport System for Alanine, Serine, Cysteine, and Similar Amino Acids

1967 • 326 citations

Partition analysis and concept of net rate constants as tools in enzyme kinetics

1975 • 323 citations

Organic ion transport during seven decades the amino acids

1984 • 284 citations

[9] Effects of pH on enzymes

1979 • 234 citations

Interorgan amino acid nutrition

1982 • 193 citations

Cationic amino acid transport into cultured animal cells. I. Influx into cultured human fibroblasts.

1982 • 185 citations

Induction of urea cycle enzymes of rat liver by glucagon.

1978 • 174 citations

Transport of Glycine by Pigeon Red Cells^*

1964 • 163 citations

Testing and characterizing the simple carrier

1974 • 152 citations

The transport of neutral amino acids in cultured human fibroblasts.

1980 • 140 citations

Cationic amino acid transport into cultured animal cells. II. Transport system barely perceptible in ordinary hepatocytes, but active in hepatoma cell lines.

1982 • 136 citations

Contrasts in transport systems for anionic amino acids in hepatocytes and a hepatoma cell line HTC.

1982 • 131 citations

Evidence for two Na+-independent neutral amino acid transport systems in primary cultures of rat hepatocytes. Time-dependent changes in activity.

1982 • 120 citations

Data for biochemical research

1961 • 119 citations

Lysine Transport across Isolated Rabbit Ileum

1969 • 113 citations

Transport of Diamino Acids into the Ehrlich Cell

1966 • 105 citations

Cationic Amino Acid Transport in the Rabbit Reticulocyte

1969 • 105 citations

Proton-sulfate co-transport: mechanism of H+ and sulfate addition to the chloride transporter of human red blood cells.

1982 • 98 citations

A stereoselective anomaly in dicarboxylic amino acid transport.

1981 • 98 citations

Elevated manganese concentration and arginase activity in livers of streptozotocin-induced diabetic rats.

1983 • 93 citations

Free amino acids in the caiman and rat

1966 • 92 citations

Glucagon: a Protein Catabolic Hormone in the Isolated Perfused Rat Liver

1960 • 89 citations

Recognition Sites for Material Transport and Information Transfer

1975 • 76 citations

Relations in the Transport of β-Alanine and the α-Amino Acids in the Ehrlich Cell

1964 • 72 citations

Discrimination of Na+-independent transport systems L, T, and asc in erythrocytes. Na+ independence of the latter a consequence of cell maturation?

1985 • 71 citations

Induction and decay of amino acid transport in the liver. Turnover of transport activity in isolated hepatocytes after stimulation by diabetes or glucagon.

1984 • 69 citations

An experimental test for cyclic versus linear transport models. The mechanisms of glucose and choline transport in erythrocytes.

1981 • 67 citations

The two-way flux of cationic amino acids across the plasma membrane of mammalian cells is largely explained by a single transport system.

1982 • 63 citations

Dibasic aminod acid transport in rat-kidney cortex slices

1967 • 63 citations

Role of System Gly in glycine transport in monolayer cultures of liver cells

1981 • 62 citations

Transport of dibasic amino acids, cystine, and tryptophan by cultured human fibroblasts: absence of a defect in cystinuria and Hartnup disease

1972 • 62 citations

Role of proton dissociation in the transport of acidic amino acids by the Ehrlich ascites tumor cells

1977 • 61 citations

A role for aminoacyl-tRNA synthetases in the regulation of amino acid transport in mammalian cell lines.

1977 • 61 citations

Regulation of active amino acid transport by growth-related changes in membrane potential in a human fibroblast.

1978 • 60 citations

Regulation of amino acid transport system L in Chinese hamster ovary cells.

1982 • 59 citations

Simultaneous regulation of amino acid influx and efflux by system A in the hepatoma cell HTC. Ouabain simulates the starvation-induced derepression of system A amino acid transport.

1983 • 58 citations

Structural Selectivity in Interaction of Neutral Amino Acids and Alkali Metal Ions with a Cationic Amino Acid Transport System

1971 • 57 citations

Liver uptake of amino acids and carbohydrates during a single circulatory passage

1975 • 51 citations

The Enzymic Pattern of Neoplastic Tissue

1967 • 50 citations

Exchange diffusion of dibasic amino acids in rat-kidney cortex slices

1967 • 47 citations

Membrane Structure and Mechanisms of Biological Energy Transduction

1973 • 45 citations

[4] Derivation of initial velocity and isotope exchange rate equations

1979 • 45 citations

Models for the active transport of cations ⋯ The steady-state analysis

1977 • 44 citations

Na+-Gradient dependence of basic amino acid transport into rat intestinal brush border membrane vesicles

1984 • 42 citations

Stimulation of basic amino acid uptake by certain neutral amino acids in isolated intestinal epithelial cells

1971 • 42 citations

Transport ofl-lysine by rat renal brush border membrane vesicles

1983 • 39 citations

Hepatic transport system interconverted by protonation from service for neutral to service for anionic amino acids.

1982 • 39 citations

Lysine transport across the small intestine. Stimulating and inhibitory effects of neutral amino acids

1980 • 38 citations

Role of the membrane potential in serum‐stimulated uptake of amino acid in a diploid human fibroblast

1977 • 38 citations

Cationic amino acid transport in chicken small intestine

1971 • 36 citations

Synthesis of metabolism-resistant substrates for the transport system for cationic amino acids; their stimulation of the release of insulin and glucagon, and of the urinary loss of amino acids related to cystinuria

1973 • 36 citations

[5] Computer-assisted derivation of steady-state rate equations

1979 • 34 citations

Comparison of system N in fetal hepatocytes and in related cell lines.

1983 • 33 citations

Reactions of neutral amino acids plus Na⁺ with a cationic amino acid transport system

1969 • 33 citations

Distinguishing transport systems having overlapping specificities for neutral and basic amino acids in the rabbit ileum.

1981 • 32 citations

Transport ofl-lysine by rat intestinal brush border membrane vesicles

1983 • 30 citations

The properties of Na+-dependent and Na+-independent lysine uptake by isolated intestinal epithelial cells

1973 • 25 citations

Heterogeneity of Na+-independent 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid and L-leucine transport in isolated rat hepatocytes in primary culture

1982 • 25 citations

Testing transport models with substrates and reversible inhibitors

1978 • 24 citations

Implications of the Cellular Transport Step for Amino Acid Metabolism

2009 • 23 citations

Exchange transport and amino acid charge as the basis for Na+-independent lysine uptake by isolated intestinal epithelial cells

1973 • 22 citations

Heterogeneity of histidine transport in the Ehrlich cell

1976 • 22 citations

Does the non-saturable cell entry apply to the charge-free form of amino acids?

1977 • 20 citations

The uptake of ornithine and lysine by isolated hepatocytes and fibroblasts

1984 • 12 citations

Naming plan for membrane transport systems for amino acids

1984 • 9 citations

Biochemical changes during carcinogenesis. IV. Protein synthesis and urea production in perfused livers of rats fed 2-acetylaminofluorene.

1960 • 8 citations